Evidence map›Paper›PMID 40561036›Full record

ArticleScience advances2025

Autonomous chemo-metabolic construction of anisotropic cell-in-shell nanobiohybrids in enzyme-powered cell microrobots.

Nayoung Kim, Sang Yeong Han, Hyeong Bin Rheem, Hojae Lee, Insung S Choi

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nayoung KimDepartment of Chemistry, KAIST, Daejeon 34141, Korea.ORCID 0009-0004-1689-8844
Sang Yeong HanDepartment of Chemistry, KAIST, Daejeon 34141, Korea.
Hyeong Bin RheemDepartment of Chemistry, KAIST, Daejeon 34141, Korea.
Hojae LeeDepartment of Chemistry, Hallym University, Chuncheon 24252, Korea.ORCID 0000-0003-1698-4414
Insung S ChoiDepartment of Chemistry, KAIST, Daejeon 34141, Korea.ORCID 0000-0002-9546-673X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Living organisms use intricate strategies to adapt and survive in response to potentially lethal environment changes. Inspired by cryptobiosis in nature, researchers have pioneered approaches to create cell-in-shell nanobiohybrids, aiming to endow cells with enhanced protection and exogenous functions. Yet, these methods still lack the biological autonomy intrinsic to natural cellular responses. Here, we present an innovative chemo-metabolically coupled strategy for the autonomous construction of cell-in-shell structures in cell growth medium. Our system harnesses ethanol fermentation by

Indexed as

Artificial CellsSaccharomyces cerevisiaeAnisotropyEthanolFermentationHorseradish PeroxidaseIndolesPolymersEthanolHorseradish PeroxidaseIndolespolydopaminePolymers

Identifiers

PMID40561036
PMCPMC12189949

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.