ArticleScience advances2025
PET-based immunomapping of intratumoral CD4
Abstract read
In one paragraph
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Granzyme B PET Imaging Reveals LgmnAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Single-cell multiomics identifies an ALDH9A1-carnitine signaling axis driving resistance of NSCLC to immunotherapy.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Stefania PezzanaWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.ORCID 0009-0004-9744-857X
Simone BlaessWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.
Bjoern TraenkleNMI Natural and Medical Sciences Institute at the University of Tuebingen, Reutlingen, Germany.ORCID 0000-0002-6106-4302
Anna SchaeferWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.
Lara RuoffWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.
Bredi TakoWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.
Salvador Castaneda VegaWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.ORCID 0000-0002-0484-9904
Philipp D KaiserNMI Natural and Medical Sciences Institute at the University of Tuebingen, Reutlingen, Germany.ORCID 0009-0003-3517-0341
Teresa WagnerNMI Natural and Medical Sciences Institute at the University of Tuebingen, Reutlingen, Germany.ORCID 0000-0002-1050-5948
Irene Gonzalez-MenendezCluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tuebingen, Tuebingen, Germany.
Leticia Quintanilla-MartinezCluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tuebingen, Tuebingen, Germany.
Alexander RochwargerDepartment of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tuebingen, University of Tuebingen, Tuebingen, Germany.ORCID 0009-0000-4272-7249
Christian M SchürchCluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tuebingen, Tuebingen, Germany.ORCID 0000-0002-1792-1768
Simon RielDepartment of Dermatology, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.ORCID 0000-0002-6618-9905
Martin SchallerDepartment of Dermatology, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.ORCID 0000-0002-7930-1919
Evelien A J van GenugtenDepartment of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands.ORCID 0000-0002-7589-4294
Iris A E van der HoornDepartment of Medical Biosciences, Radboud University Medical Center, Nijmegen, Netherlands.ORCID 0009-0008-8644-0678
Mark A J GorrisDepartment of Medical Biosciences, Radboud University Medical Center, Nijmegen, Netherlands.ORCID 0000-0003-3621-226X
Megan SteinvoortDepartment of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands.
Eva PeetersDepartment of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands.
I Jolanda M de VriesDepartment of Medical Biosciences, Radboud University Medical Center, Nijmegen, Netherlands.ORCID 0000-0002-8653-4040
Michel M van den HeuvelDepartment of Pulmonology, Radboud University Medical Center, Nijmegen, Netherlands.ORCID 0000-0002-6372-2153
Erik H J G AarntzenDepartment of Nuclear Medicine, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.ORCID 0000-0002-3809-0182
Andreas MaurerWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.ORCID 0000-0003-2412-5361
Ulrich RothbauerPharmaceutical Biotechnology, University of Tuebingen, Tuebingen, Germany.ORCID 0000-0001-5923-8986
Bernd J PichlerWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.ORCID 0000-0001-6784-5524
Manfred KneillingWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.
Dominik SonaniniWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Germany.ORCID 0000-0002-7085-0161
Funding
No grant is acknowledged in the PubMed record.
Abstract
CD4
Indexed as
Carcinoma, Non-Small-Cell LungCD4-Positive T-LymphocytesDrug Resistance, NeoplasmImmune Checkpoint InhibitorsPositron-Emission TomographyAnimalsCell Line, TumorCopper RadioisotopesHumansImmunotherapyLung NeoplasmsMiceSingle-Domain AntibodiesT-Lymphocytes, RegulatoryCopper-64Copper RadioisotopesImmune Checkpoint InhibitorsSingle-Domain Antibodies
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.