Evidence map›Paper›PMID 40560951›Full record

ArticlePhysiological reports2025

The physiological effects of breath-holding during high-intensity exercise.

Jeremy Walsh, James L Ramsey, Nasimi A Guluzade, Robin Faricier, Daniel A Keir, Glen R Belfry

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeremy WalshSchool of Kinesiology, Western University, London, Ontario, Canada.ORCID 0000-0002-1019-0018
James L RamseySchool of Kinesiology, Western University, London, Ontario, Canada.
Nasimi A GuluzadeSchool of Kinesiology, Western University, London, Ontario, Canada.
Robin FaricierSchool of Kinesiology, Western University, London, Ontario, Canada.
Daniel A KeirSchool of Kinesiology, Western University, London, Ontario, Canada.
Glen R BelfrySchool of Kinesiology, Western University, London, Ontario, Canada.ORCID 0000-0002-8831-2652

Funding

National Sciences and Engineering Research Council of Canada (NSERC) CGS D 5796622023
6 · The paper itself

Abstract

The purpose of this study was to determine the physiological effects of breath-holding during high-intensity exercise. Twenty participants (age: 23 ± 4 years, 10 females) performed 20 s sprints of simultaneous arm and leg ergometry exercise, under free-breathing (FB) and breath-holding (BH) conditions. Identical power outputs were sustained for both breathing conditions. Heart rate was significantly higher under the breath-holding condition during exercise (FB = 118 ± 12 bpm versus BH = 131 ± 14 bpm; p < 0.001) but lower for 5 min post-exercise (FB = 110 ± 16 bpm, BH = 102 ± 15 bpm, p = 0.003). Systolic blood pressure was higher under the breath-holding condition post-exercise (FB = 142 ± 18 mmHg, BH = 151 ± 15 mmHg, p = 0.03). Muscle deoxygenated hemoglobin was unchanged between conditions during exercise (FB = 2.7 ± 1.7 μM, BH = 2.6 ± 1.7 μM, p = 0.37) and no difference in post-exercise blood lactate concentration was observed between conditions (FB = 9.3 ± 3.5 mmol.L

Indexed as

Breath HoldingExerciseAdultBlood PressureFemaleHeart RateHumansLactic AcidMaleOxygen ConsumptionYoung AdultLactic Acidapneabreath‐holdingexercisehigh‐intensity

Identifiers

PMID40560951
PMCPMC12190552

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.