Evidence map›Paper›PMID 40560935›Full record

SynthesisPloS one2025

Effects of maternal anemia on low-birth-weight in Sub-Sahara African countries: Systematic review and meta-analysis.

Nigus Kabtu Belete, Abebe Gedefaw Belete, Darik Temesgen Assefa, Muluken Bekele Sorrie, Manaye Yihune Teshale

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nigus Kabtu BeleteDepartment of public health, College of Medicine and Health Science, Arba Minch University, Arbaminch, Ethiopia.ORCID 0000-0002-9838-6583
Abebe Gedefaw BeleteDepartment of public health, College of Medicine and Health Science, Arba Minch University, Arbaminch, Ethiopia.
Darik Temesgen AssefaDepartment of public health, College of Medicine and Health Science, Arba Minch University, Arbaminch, Ethiopia.ORCID 0009-0001-3753-4845
Muluken Bekele SorrieDepartment of public health, College of Medicine and Health Science, Arba Minch University, Arbaminch, Ethiopia.
Manaye Yihune TeshaleDepartment of public health, College of Medicine and Health Science, Arba Minch University, Arbaminch, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMaternal anemia is a major public health concern that affects women globally, with a particularly high prevalence in developing countries, notably in sub-Saharan Africa. This condition is linked to negative birth outcomes, with low birth weight being a common consequence of maternal anemia during pregnancy. Therefore, this study aims to evaluate the effect of maternal anemia on low birth weight in the context of sub-Saharan African countries.

methodsThis study involved searching electronic databases, including PubMed, Embase, Scopus, Cochrane, and Web of Science, as well as reference lists and citation tracking for additional studies. It included cohort, case control, and cross-sectional studies published in English between January 2015 and June 2024. Data were extracted using Covidence and transferred to Microsoft Excel, then to Stata™ Version 17.0 for analysis. Heterogeneity was assessed with forest plots and the Inverse variance (I2) test. Subgroup analysis, sensitivity analysis, and meta-regression were performed to explore sources of heterogeneity, while funnel plot symmetry was evaluated for publication bias. The meta-analytic effect was summarized using pooled odds ratios, 95% confidence intervals, and I2 tests for heterogeneity. This was registered on the PROSPERO under the identification number CRD42024561098.

resultA total of 1213 articles were identified, 71 of which were screened for full-text review, and 21 involving women from sub-Saharan African countries met the inclusion criteria, and were included in this meta-analysis. Women with anemia during pregnancy are at higher risk of giving birth to babies with low birth weight compared to women without anemia (AOR = 3.37; 95% CI: 2.66-4.27; I2: 96.71%).

conclusionMaternal anemia during pregnancy was identified as a significant risk factor for low birth weight. Such that the incidence of low birth weight could possibly be reduced with early identification and proper care of anemia during pregnancy.

Indexed as

AnemiaInfant, Low Birth WeightPregnancy Complications, HematologicAfrica South of the SaharaFemaleHumansInfant, NewbornPregnancy

Identifiers

PMID40560935
PMCPMC12192055

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.