Evidence map›Paper›PMID 40560539›Full record

ArticleJournal of biomechanical engineering2025

Contributions of Muscle Forces to Stability and Mobility in Radiography-Driven Models of Total Shoulder Arthroplasty.

Brendan M Curran, Casey A Myers, Peter J Laz, Thor E Andreassen, Kevin B Shelburne

Abstract read
In one paragraph

Article in Journal of biomechanical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brendan M CurranDepartment of Mechanical Engineering, University of Denver, 2155 East Wesley Avenue, Denver, CO 80208.
Casey A MyersDepartment of Mechanical Engineering, University of Denver, 2155 East Wesley Avenue, Denver, CO 80208.
Peter J LazDepartment of Mechanical Engineering, University of Denver, 2155 East Wesley Avenue, Denver, CO 80208.
Thor E AndreassenMayo Clinic, Assistive and Restorative Technology Laboratory, 200 1st Street SW Rochester, MN 55905.ORCID 0000-0002-9787-7890
Kevin B ShelburneDepartment of Mechanical Engineering, University of Denver, 2155 East Wesley Avenue, Denver, CO 80208.

Funding

Musculoskeletal Research Training ProgramT32AR056950 · NIAMS · MAYO CLINIC ROCHESTER · PI Jennifer J Westendorf · 2009 to 2026
$7.0M
A Lower Extremity Neuromusculoskeletal Human Simulator: Addressing Multiscale ChallengesU01AR072989 · NIAMS · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI SHELBURNE, KEVIN B · 2018 to 2021
$1.9M
NIAMS NIH HHS T32 AR056950NIAMS NIH HHS U01 AR072989
6 · The paper itself

Abstract

Several complications are associated with total shoulder arthroplasty (TSA), including glenoid loosening and joint instability. These complications are linked to imbalances in glenohumeral muscle forces, which cause eccentric loading that occurs on the outer edge of the glenoid component, rather than in the center of the glenoid, and can be damaging to the implant and destabilizing the joint. The purpose of this study was to develop musculoskeletal models of TSA patients using their skeletal geometry acquired from CT and their kinematics acquired with high-speed stereo radiography (HSSR) to predict glenohumeral joint loading and muscle forces for abduction and flexion and describe how these loads differ from their native contralateral side. CT data was collected for both shoulders of 6 TSA patients (three anatomic and three reverse). Models were developed using CT reconstructions of each patient's scapula and humerus, and placed implant geometry with CT-derived alignment. Mesh morphing was used to create personalized muscle attachment sites on the scapula. Simulation of abduction and flexion to quantify muscle and joint forces was driven with limb-specific HSSR kinematics. At 90 deg abduction, reverse TSA increased superior shear force by 11.2% bodyweight (BW) and decreased medial compressive force by 27.5%BW compared to each patient's contralateral shoulder. Lateral deltoid elevation moment arms and stability ratios increased 9.61 mm and 0.58, respectively. At 90 deg abduction, anatomic TSA patients increased humeral internal rotation by 52.7 deg and decreased rotator cuff force by 9.4%BW. Patient-specific musculoskeletal models quantified differences in glenohumeral joint mechanics. This study revealed muscle and kinematic mechanisms that could lead to edge loading and glenoid loosening in TSA and can inform personalized surgical planning for implant alignment with the goal of improving patient outcomes.

Indexed as

Arthroplasty, Replacement, ShoulderMechanical PhenomenaModels, BiologicalMuscle, SkeletalShoulder JointAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedRange of Motion, ArticularTomography, X-Ray Computed

Identifiers

PMID40560539
PMCPMC13148771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.