ReviewChemistry (Weinheim an der Bergstrasse, Germany)2025
Advances in Copper and Nickel C─N and C─O Cross-Couplings of (Hetero)Aryl Chlorides Enabled by Ancillary Ligand Development.
Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Mechanism-Inspired Ligand Design for Efficient Copper-Catalyzed C-N Coupling of Aryl and Heteroaryl Chlorides.Journal of the American Chemical Society · 2026Article
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Authors and funding
2 authors.
Funding
Abstract
The evolution of palladium-catalyzed C─N and C─O cross-coupling chemistry into first-choice methods for the synthesis of aniline and phenol derivatives can be attributed to innovations in ancillary ligand design that facilitate challenging elementary steps of thermal catalysis. Inspired by this strategy, and in the quest to establish more sustainable thermal base metal catalysis that is competitive with and complementary to such precious metal protocols, several successful mechanism-inspired ancillary ligand classes for use in enabling high-performing copper and nickel catalysts have emerged over the last decade. In this Review we document key ancillary ligand advances of this type, with a focus on superlative copper and nickel catalysts that enable C─N or C─O cross-couplings of cheap and abundant (hetero)aryl chloride electrophiles under operationally simple conditions of relevance to end-users in academia and industry.
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Registered trials
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