Evidence map›Paper›PMID 40560473›Full record

ArticleProbiotics and antimicrobial proteins2026

Highly Active Probiotic Yogurt Against Cyclophosphamide-Induced Immunosuppression in Mice by Regulating Immune Response and Gut Microbiota.

Liyuan Yun, Jinpeng Zhang, Tiantian Zhao, Qian Li, Shuguang Fang, Xiaojuan Guo, Yanfeng Wu, YunJiao Zhao, Min Zhang

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liyuan YunCollege of Food Science and Bioengineering, Tianjin Agricultural University, Tianjin, 300392, China.
Jinpeng ZhangCollege of Food Science and Bioengineering, Tianjin Agricultural University, Tianjin, 300392, China.
Tiantian ZhaoCollege of Food Science and Bioengineering, Tianjin Agricultural University, Tianjin, 300392, China.
Qian LiCollege of Food Science and Bioengineering, Tianjin Agricultural University, Tianjin, 300392, China.
Shuguang FangWecare Probiotics Co., Ltd, Suzhou, 215200, China.
Xiaojuan GuoWecare Probiotics Co., Ltd, Suzhou, 215200, China.
Yanfeng WuWecare Probiotics Co., Ltd, Suzhou, 215200, China.
YunJiao ZhaoWecare Probiotics Co., Ltd, Suzhou, 215200, China.
Min ZhangCollege of Food Science and Bioengineering, Tianjin Agricultural University, Tianjin, 300392, China. zm0102@tust.edu.cn.

Funding

2024 Tianjin "the Belt and Road" Innovation Platform Project 24PTLYHZ00020the National Key Research and Development Program of China 2022YFF1100201the National Natural Science Foundation of China 32172169the Open Fund of Tianjin Key Laboratory of Intelligent Breeding of Major Crops KLIBMC2312the Tianjin "131" Innovative Talent Team Project 201926
6 · The paper itself

Abstract

Probiotics play a crucial role in modulating the immune system and maintaining intestinal epithelial barrier integrity. The study investigates the effects of high-activity probiotic yogurt on immunosuppressed mice induced by cyclophosphamide (CTX). ICR male mice (8-week-old) were injected intraperitoneally with CTX (80 mg/kg body weight/day) on days 7, 8, and 9 to establish an immunosuppressive model (n = 10). Mice were fed a normal diet or high-activity probiotic yogurt for consecutive 14 days. The effect of three high-activity probiotic yogurt(10

Indexed as

CyclophosphamideGastrointestinal MicrobiomeProbioticsYogurtAnimalsImmunosuppression TherapyMaleMiceMice, Inbred ICRNF-kappa BToll-Like Receptor 4CyclophosphamideNF-kappa BToll-Like Receptor 4CyclophosphamideGut microbiotaHigh-activity probioticImmune responseYogurt

Identifiers

PMID40560473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.