GuidelineZeitschrift fur Rheumatologie2025
[S2e guidelines on the treatment of polymyalgia rheumatica: update 2024 : Evidence-based guidelines of the German Society for Rheumatology and Clinical Immunology (DGRh), the Austrian Society for Rheumatology and Rehabilitation (ÖGR) and the Swiss Society for Rheumatology (SGR) and the participating medical scientific specialist societies and other organizations].
Guideline in Zeitschrift fur Rheumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- [Polymyalgia rheumatica].Zeitschrift fur Rheumatologie · 2026Review
- Treatment strategies in giant cell arteritis and polymyalgia rheumatica: beyond glucocorticoids.Nature reviews. Rheumatology · 2026Review
- [Does polymyalgia rheumatica with normal CRP and ESR exist, and how should it be treated?]Zeitschrift fur Rheumatologie · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polymyalgia rheumatica (PMR) is part of a disease spectrum that includes giant cell arteritis and is the second most frequent inflammatory rheumatic disease in old age, after rheumatoid arthritis (RA). The S3 guideline on the treatment of PMR published in 2018 has now been updated in the form of S2e-guidelines. The basis for the update was a systematic literature search that covered the evidence published in the period July 2016 to January 2024 on therapeutic interventions and prognostic factors for PMR. The same clinical questions and search strings as in the literature search for the original guideline were used, with an extension to also include targeted synthetic disease-modifying antirheumatic drugs (DMARDs). Based on the evidence and expert opinions, the guidelines committee (12 physicians, 2 healthcare professionals and 2 patients from 3 countries) developed a total of 7 recommendations. In addition to updating the contents, some recommendations were restructured by summarizing or separating them with the aim of simplifying the applicability compared to the 2018 guidelines. It is still recommended to initiate treatment with glucocorticoids (15-25 mg prednisone equivalents per day) immediately after diagnosis and subsequently to taper these drugs while monitoring the disease activity and adverse effects of the treatment. Interleukin‑6 receptor blocking agents (alternatively, methotrexate or rituximab may be considered) should be used in addition to glucocorticoids in patients with relapsing disease, and these drugs can be considered in individual cases with new-onset PMR and high risk for glucocorticoid-related adverse events. Older and/or frail patients should be offered an individualized exercise program in addition to drug therapy. This updated guideline should serve as an aid to making evidence-based decisions in order to ensure standardized high-quality care for all patients with PMR.
Indexed as
Identifiers
40560440What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.