Evidence map›Paper›PMID 40560390›Full record

ReviewDer Nervenarzt2026

[Youth mental health: early detection and early intervention of mental disorders].

Peter J Uhlhaas, Andreas Bechdolf, Kerstin Konrad, Nikolaos Koutsouleris, Eva Meisenzahl, Andreas Meyer-Lindenberg, Ulrich Reininghaus, Christoph U Correll

Abstract readEnglish AbstractReview
In one paragraph

Review in Der Nervenarzt, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peter J UhlhaasDepartment of Child and Adolescent Psychiatry, Charité-Universitätsmedizin, Berlin, Deutschland. peter.uhlhaas@charite.de.
Andreas BechdolfGerman Center for Mental Health (DZPG), partner site Berlin-Potsdam, Berlin, Deutschland.
Kerstin KonradChild Neuropsychology Section, Department of Child and Adolescent Psychiatry, RWTH, Aachen, Deutschland.
Nikolaos KoutsoulerisDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, München, Deutschland.
Eva MeisenzahlDepartment of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, LVR Düsseldorf, Düsseldorf, Deutschland.
Andreas Meyer-LindenbergCentral Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Deutschland.
Ulrich ReininghausGerman Center for Mental Health (DZPG), partner site Mannheim-Heidelberg-Ulm, Mannheim, Deutschland.
Christoph U CorrellDepartment of Child and Adolescent Psychiatry, Charité-Universitätsmedizin, Berlin, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMental diseases occur particularly frequently between the ages of 12 and 25 years, with important implications for the pathogenesis, diagnosis and treatment.

objectiveAgainst this background this article outlines a youth mental health paradigm which prioritizes the early detection, early intervention and prevention of mental disorders, e.g., psychoses, bipolar disorders and personality disorders in adolescence. MATERIAL AND

methodsThe first part of the article summarizes the findings for sensitive phases during brain development, which indicate the elevated plasticity of neural circuits during youth that can be used for preventive interventions. The interactions between risk and resilience factors and ongoing brain development are an essential reason for the frequent occurrence of mental disorders between 12-25 years. Furthermore, innovative diagnostic approaches, such as clinical staging models, are proposed that are a prerequisite for early detection and early intervention. In this context, low-threshold service modelss and age-appropriate interventions, such as digital approaches, are necessary to improve access to care in youths. DISCUSSION: Taken together, a "youth mental health" paradigm could significantly enhance mental health in young people and initiate a shift towards the prevention of severe mental disorders.

Indexed as

Early Medical InterventionMental DisordersAdolescentAdultBrainChildEarly DiagnosisEvidence-Based MedicineFemaleGermanyHumansMaleYoung AdultAdolescenceEarly detectionEarly interventionSensitive phasesYouth mental health

Identifiers

PMID40560390
PMCPMC13171657

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.