Evidence map›Paper›PMID 40560275›Full record

ArticleAnalytical and bioanalytical chemistry2025

Bioanalysis of monodisperse HO-PEG

Luyao Yu, Meichen Liu, Ziyi Niu, Jiarui Zhang, Yue Deng, Xinyue Zhou, Jiansong You, Hongyu Xue, Lei Yin, Meiyun Shi

Abstract read
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Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luyao YuCancer Hospital of Dalian University of Technology, Dalian University of Technology, Shenyang, 110042, People's Republic of China.
Meichen LiuSchool of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, 124221, People's Republic of China.
Ziyi NiuSchool of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, 124221, People's Republic of China.
Jiarui ZhangSchool of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, 124221, People's Republic of China.
Yue DengSchool of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, 124221, People's Republic of China.
Xinyue ZhouSchool of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, 124221, People's Republic of China.
Jiansong YouSchool of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, 124221, People's Republic of China.
Hongyu XueSchool of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, 124221, People's Republic of China. hongyuxue@dlut.edu.cn.
Lei YinSchool of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, 124221, People's Republic of China. leiyin@dlut.edu.cn.
Meiyun ShiCancer Hospital of Dalian University of Technology, Dalian University of Technology, Shenyang, 110042, People's Republic of China. shimy@dlut.edu.cn.

Funding

open funding of Cancer Hospital of Dalian University of Technology 2024-ZIKF-33the Fundamental Research Funds for the Central Universities DUT23YG228the Fundamental Research Funds for the Central Universities DUT24MS018the Natural Science Foundation of Liaoning Province 2023-MSBA-018
6 · The paper itself

Abstract

Monodisperse polyethylene glycol (PEG) derivatives offer significant advantages over conventional polydisperse PEGs for biomedical applications due to their precisely defined molecular structures. This study establishes an eco-efficient, selective, and sensitive analytical assay integrating microscale solid-phase extraction (μ-SPE) with ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) to investigate the cellular uptake of HO-PEG

Indexed as

Green Chemistry TechnologyPolyethylene GlycolsSolid Phase ExtractionSolid Phase MicroextractionTandem Mass SpectrometryChromatography, High Pressure LiquidHumansLimit of DetectionMCF-7 CellsReproducibility of ResultsPolyethylene GlycolsCellular pharmacokineticsGreen analytical chemistryMethod validationMicro-solid-phase extractionMonodisperse polyethylene glycol

Identifiers

PMID40560275

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.