ArticleClinical oral investigations2025
Effect of laser applications with different agents on dentin surface roughness, bacterial adhesion and tubule occlusion.
Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Research Progress on Mechanisms of Milk-Derived Functional Components in Regulating Bone Health and the Gut-Bone Axis.Nutrients · 2026Review
- Effect of eggshell nanoparticles and fluoride varnish, with and without diode laser, on dentinal tubule occlusion (An in vitro study).BMC oral health · 2026Article
- One-Year Clinical Performance of Injectable and Paste-Type Composite Resins in Non-Carious Cervical Lesions Prepared with Er,Cr:YSGG Laser and Acid Etching: A Randomized Clinical Trial.Journal of functional biomaterials · 2026Article
- Evaluation and comparison of the efficacy of the diode laser and Biodentine on dentinal tubule occlusion.Journal of oral biology and craniofacial researchArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to evaluate the effects of laser application with different agents on dentin surface roughness, tubule occlusion, and bacterial adhesion in vitro. MATERIALS AND
methodsA total of 216 dentin blocks from bovine incisors were divided into nine groups. Treatments included 5% sodium fluoride (NaF) varnish, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), Er, Cr: YSGG laser, and diode laser in various combinations. Surface roughness (SR) was measured using a profilometer. S. mutans and S. mitis suspensions were incubated for 24 h, and bacterial adhesion was quantified (×10⁸ Cfu/ml) and visualized using confocal laser scanning microscopy. Tubule occlusion was assessed via SEM imaging and analyzed with ImageJ software. Statistical analysis was performed using one-way ANOVA and Tukey HSD (p = 0.05).
resultsExcept for the CPP-ACP groups treated with laser, all groups exhibited significantly higher surface roughness (p < 0.05); however, this did not influence bacterial adhesion (p > 0.05). All treatments significantly reduced the number and diameter of open dentinal tubules (p < 0.05). The combination of NaF with Er, Cr: YSGG and diode laser enhanced tubule occlusion, while CPP-ACP with laser had no additional effect.
conclusionsIncreased surface roughness, except in CPP-ACP with laser groups, did not affect bacterial adhesion. All desensitization methods effectively promoted tubule occlusion, with the diode laser demonstrating greater efficacy than the Er, Cr: YSGG laser. CLINICAL SIGNIFICANCE: Lasers should be used with caution as they may increase the roughness of the dentin surface. The combined application of NaF with lasers may improve its clinical efficacy.
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