Evidence map›Paper›PMID 40560044›Full record

ArticleRadiology. Artificial intelligence2025

High-Performance Open-Source AI for Breast Cancer Detection and Localization in MRI.

Lukas Hirsch, Elizabeth J Sutton, Yu Huang, Beliz Kayis, Mary Hughes, Danny Martinez, Hernan A Makse, Lucas C Parra

Abstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Lukas HirschDepartment of Biomedical Engineering, City College of the City University of New York, 160 Convent Ave, New York, NY 10031.ORCID 0000-0003-3173-9142
Elizabeth J SuttonDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-1407-7012
Yu HuangDepartment of Biomedical Engineering, City College of the City University of New York, 160 Convent Ave, New York, NY 10031.ORCID 0000-0003-4178-0739
Beliz KayisDepartment of Biomedical Engineering, City College of the City University of New York, 160 Convent Ave, New York, NY 10031.ORCID 0009-0001-8387-877X
Mary HughesDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-4168-677X
Danny MartinezDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-8564-9049
Hernan A MakseLevich Institute and Department of Physics, City College of the City University of New York, New York, NY.
Lucas C ParraDepartment of Biomedical Engineering, City College of the City University of New York, 160 Convent Ave, New York, NY 10031.ORCID 0000-0003-4667-816X

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Machine learning for risk-adjusted breast MRI screeningR01CA247910 · NCI · CITY COLLEGE OF NEW YORK · PI PARRA, LUCAS C, SUTTON, ELIZABETH J · 2021 to 2025
$3.3M
Application of the principle of symmetry to neural circuitry: From building blocks to neural synchronization in the connectomeR01EB028157 · NIBIB · CITY COLLEGE OF NEW YORK · PI MAKSE, HERNAN, ZIMMER, MANUEL · 2020 to 2020
$1.1M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA247910NIBIB NIH HHS R01 EB028157
6 · The paper itself

Abstract

Purpose To develop and evaluate an open-source deep learning model for detection and localization of breast cancer on MRI scans. Materials and Methods In this retrospective study, a deep learning model for breast cancer detection and localization was trained on the largest breast MRI dataset to date. Data included all breast MRI examinations conducted at a tertiary cancer center in the United States between 2002 and 2019. The model was validated on sagittal MRI scans from the primary site (

Indexed as

Breast NeoplasmsDeep LearningImage Interpretation, Computer-AssistedMagnetic Resonance ImagingAdultBreastFemaleHumansMiddle AgedRetrospective StudiesSensitivity and SpecificityBreastComputer-aided Diagnosis (CAD)MRINeural Networks

Identifiers

PMID40560044
PMCPMC12464713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.