Evidence map›Paper›PMID 40560008›Full record

ReviewTomography (Ann Arbor, Mich.)2025

Development of Cardiac Computed Tomography for Evaluation of Aortic Valve Stenosis.

Hiroyuki Takaoka, Haruka Sasaki, Joji Ota, Yoshitada Noguchi, Moe Matsumoto, Kazuki Yoshida, Katsuya Suzuki, Shuhei Aoki, Satomi Yashima, Makiko Kinoshita and 2 more

Abstract readReview
In one paragraph

Review in Tomography (Ann Arbor, Mich.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hiroyuki TakaokaDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.ORCID 0000-0001-8745-2162
Haruka SasakiDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Joji OtaDepartment of Radiology, Chiba University Hospital, Chiba 260-8677, Japan.
Yoshitada NoguchiDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Moe MatsumotoDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Kazuki YoshidaDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.ORCID 0000-0002-1692-4107
Katsuya SuzukiDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Shuhei AokiDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Satomi YashimaDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Makiko KinoshitaDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Noriko Suzuki-EguchiDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
Yoshio KobayashiDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.

Funding

Japan Society for the Promotion of Science Grant Number: JP24K21117, JP23K11891, and JP23K11824
6 · The paper itself

Abstract

Aortic valve stenosis (AS) is a valvular heart disease that imposes a high afterload on the left ventricle (LV) due to restricted opening of the aortic valve, resulting in LV hypertrophy. Severe AS can lead to syncope, angina pectoris, and heart failure. The number of patients with AS has been increasing due to aging populations, the growing prevalence of lifestyle-related diseases, and advances in diagnostic technologies. Therefore, accurate diagnosis and appropriate treatment of AS are essential. In recent years, transcatheter aortic valve implantation (TAVI) has become feasible, and the number of procedures has rapidly increased, particularly among elderly patients. As treatment options for AS expand and diversify, detailed pre-procedural evaluation has become increasingly important. In particular, diagnostic imaging modalities such as computed tomography (CT) have advanced significantly, with notable improvements in image quality. With recent advancements in CT technology-such as increased detector rows, faster gantry rotation speeds, new image reconstruction methods, and the introduction of dual-energy imaging-the scope of cardiac assessment has expanded beyond the coronary arteries to include valves, myocardium, and the entire heart. This includes evaluating restricted AV opening and cardiac function using four-dimensional imaging, assessing AV annulus diameter and AS severity via calcium scoring with a novel motion correction algorithm, and detecting myocardial damage through late-phase contrast imaging using new reconstruction techniques. In cases of pre-TAVI evaluation or congenital bicuspid valves, CT is also valuable for assessing extracardiac structures, such as access routes and associated congenital heart anomalies. In addition, recent advancements in CT technology have made it possible to significantly reduce radiation exposure during cardiac imaging. CT has become an extremely useful tool for comprehensive cardiac evaluation in patients with aortic stenosis, especially those being considered for surgical treatment.

Indexed as

Aortic Valve StenosisTomography, X-Ray ComputedAortic ValveHumansTranscatheter Aortic Valve Replacementaortic stenosiscomputed tomographycoronary artery

Identifiers

PMID40560008
PMCPMC12196544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.