Evidence map›Paper›PMID 40559860›Full record

ReviewToxins2025

INM004: Polyclonal Neutralizing Antibodies Against Shiga Toxin as a Treatment for Hemolytic Uremic Syndrome.

Marta Rivas, Mariana Pichel, Vanesa Zylberman, Mariana Colonna, Marina Valerio, Carolina Massa, Romina Pardo, Andrés E Ciocchini, Santiago Sanguineti, Ian Roubicek and 2 more

Abstract readReview
In one paragraph

Review in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marta RivasInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.
Mariana PichelInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.
Vanesa ZylbermanInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.
Mariana ColonnaInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.ORCID 0000-0002-3095-1312
Marina ValerioInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.
Carolina MassaInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.
Romina PardoInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.
Andrés E CiocchiniConsejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Godoy Cruz 2290, Ciudad Autonoma de Buenos Aires 1425, Argentina.
Santiago SanguinetiInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.
Ian RoubicekInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.
Linus SpatzInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.
Fernando Alberto GoldbaumInmunova S.A., Av. 25 de Mayo 1021, San Martín, Buenos Aires 1650, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury (AKI). Shiga toxin (Stx)-producing

Indexed as

Antibodies, NeutralizingEscherichia coli InfectionsHemolytic-Uremic SyndromeShiga ToxinAnimalsHumansShiga-Toxigenic Escherichia coliAntibodies, NeutralizingShiga Toxindiagnosishemolytic uremic syndromeimmunotherapy treatmentShiga toxinSTEC-HUSvaccine development

Identifiers

PMID40559860
PMCPMC12197620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.