Evidence map›Paper›PMID 40559786›Full record

ArticleVeterinary sciences2025

Evaluation of the Immune Effect of a Trivalent Fowl Adenovirus Inactivated Vaccine Against FAdV-4/8a/8b.

Yulan Jiao, Qianhui Zhao, Yulong Zhao, Yingjie Li, Sumin Pan, Yinming Li, Yuntao Liu, Wanyu Shi

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yulan JiaoCollege of Veterinary Medicine, Hebei Agricultural University, Baoding 071001, China.
Qianhui ZhaoCollege of Veterinary Medicine, Hebei Agricultural University, Baoding 071001, China.
Yulong ZhaoRingpu (Baoding) Biological Pharmaceutical Co., Ltd., Baoding 071000, China.
Yingjie LiVeterinary Drug and Feed Work Station of Hebei Province, Shijiazhuang 050011, China.
Sumin PanCollege of Animal Science and Technology, Hebei Normal University of Science and Technology (HNUST), Qinhuangdao 066004, China.
Yinming LiCollege of Foreign Language, Hebei Agricultural University, Baoding 071001, China.
Yuntao LiuRingpu (Baoding) Biological Pharmaceutical Co., Ltd., Baoding 071000, China.
Wanyu ShiCollege of Veterinary Medicine, Hebei Agricultural University, Baoding 071001, China.

Funding

Central Guide Local Science and Technology Development Fund Project of Hebei Province 246Z6606GNational Natural Science Foundation of China 32402932
6 · The paper itself

Abstract

Fowl adenovirus can cause various diseases such as hepatitis-hydropericardium syndrome (HHS) and inclusion body hepatitis (IBH), which leads to huge economic losses for China's poultry industry. In recent years, the prevalence of FAdV-4, FAdV-8a, and FAdV-8b has been on the rise. In this study, a trivalent fowl adenovirus inactivated vaccine against FAdV-4/8a/8b was generated and the immune effect was evaluated. The results showed that chickens immunized with the trivalent vaccine could effectively resist the challenge of virulent strains of FAdV-4, FAdV-8a, and FAdV-8b. All chickens in the immunized groups survived after virus injection, gained weight normally, and the lesions in tissues and organs (liver, spleen, kidney, etc.) were significantly decreased compared with the control group. The viral load in the liver of the immunized group was significantly lower than that of the challenge control group five days after the challenge (

Indexed as

fowl adenovirusHHSIBHimmune protectioninactivated vaccineneutralizing antibody

Identifiers

PMID40559786
PMCPMC12197386

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.