Evidence map›Paper›PMID 40559696›Full record

ArticleSports (Basel, Switzerland)2025

Comparison of Hormonal, Inflammatory, Muscle Damage and Oxidative Stress Biomarkers Changes in Response to High-Intensity Interval, Circuit and Concurrent Exercise Bouts.

Francisco Javier Martínez-Noguera, Linda H Chung, Amelia Guadalupe-Grau, Silvia Montoro-García, Pedro E Alcaraz

Abstract read
In one paragraph

Article in Sports (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francisco Javier Martínez-NogueraResearch Center for High Performance Sport, Catholic University of Murcia (UCAM), Guadalupe, 30107 Murcia, Spain.ORCID 0000-0002-2851-9029
Linda H ChungResearch Center for High Performance Sport, Catholic University of Murcia (UCAM), Guadalupe, 30107 Murcia, Spain.ORCID 0000-0001-5899-9097
Amelia Guadalupe-GrauGENUD Toledo Research Group, Faculty of Sport Sciences, University of Castilla-La Mancha, 45071 Toledo, Spain.ORCID 0000-0003-2573-4572
Silvia Montoro-GarcíaPreclinical Research of Bioactive Compounds and Drugs (PREBIOF), Izpisúa Lab HiTech, Faculty of Health Sciences, Catholic University of Murcia (UCAM), Campus los Jerónimos, 30107 Murcia, Spain.ORCID 0000-0002-1948-1022
Pedro E AlcarazResearch Center for High Performance Sport, Catholic University of Murcia (UCAM), Guadalupe, 30107 Murcia, Spain.ORCID 0000-0002-9792-6656

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough chronic resting hormonal changes were traditionally considered to modulate muscle tissue remodeling and growth, our knowledge of exercise on the acute post-exercise hormonal response is limited. Moreover, the type of exercise protocol may trigger different hormonal profiles. The aim of this study was to evaluate changes in muscle damage, as well as hormonal and inflammatory markers following the response to three different resistance training protocols.

methodsA crossover study was conducted in which 33 recreationally active men were randomly assigned to three different training groups: high-intensity interval training (HIIT), concurrent training (CT), and high-intensity resistance circuit (HRC) training. Blood biomarkers were measured by standard procedures at rest, after exercise (P0), 30 min (P1), 24 h (P24), and 48 h (P48) after exercise.

resultsRegarding testosterone, the Friedman test detected a significant time × group interaction (

conclusionsHRC generates higher levels of testosterone than HIIT in the acute (P1) and late (P48) phases of recovery and produces lower levels of myostatin than CT and HIIT (P1) in the acute phase of recovery.

Indexed as

IL-6myostatinresistance trainingtestosteroneTNF-α

Identifiers

PMID40559696
PMCPMC12197150

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.