Evidence map›Paper›PMID 40559649›Full record

ArticleMarine drugs2025

Sustainable Extraction of Prospective Cosmetic Ingredients from Colombian Marine Macroalgae Using Natural Deep Eutectic Solvents.

Verónica María Tamayo-Rincón, Jhonny Colorado-Ríos, Didier Johan Alvarez-Bustamante, Vanessa Urrea-Victoria, Diana Margarita Márquez-Fernández, Constain H Salamanca, Stefano Dall'Acqua, Leonardo Castellanos-Hernandez, Alejandro Martínez-Martínez

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Verónica María Tamayo-RincónGrupo Productos Naturales Marinos, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Calle 70 No. 52-21, Medellín 050010, Colombia.
Jhonny Colorado-RíosGrupo Productos Naturales Marinos, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Calle 70 No. 52-21, Medellín 050010, Colombia.ORCID 0000-0002-5866-725X
Didier Johan Alvarez-BustamanteGrupo Productos Naturales Marinos, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Calle 70 No. 52-21, Medellín 050010, Colombia.ORCID 0009-0003-1295-3378
Vanessa Urrea-VictoriaDepartamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Sede Bogotá, Av. Carrera 30 # 45-03, Bogotá 111321, Colombia.ORCID 0000-0002-5049-7102
Diana Margarita Márquez-FernándezGrupo Productos Naturales Marinos, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Calle 70 No. 52-21, Medellín 050010, Colombia.
Constain H SalamancaGrupo de Investigación Biopolimer, Departamento de Farmacia, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Calle 70 No. 52-21, Medellín 050010, Colombia.ORCID 0000-0003-1587-5371
Stefano Dall'AcquaDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35121 Padova, Italy.ORCID 0000-0001-8264-6953
Leonardo Castellanos-HernandezDepartamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Sede Bogotá, Av. Carrera 30 # 45-03, Bogotá 111321, Colombia.ORCID 0000-0001-5248-800X
Alejandro Martínez-MartínezGrupo Productos Naturales Marinos, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Calle 70 No. 52-21, Medellín 050010, Colombia.

Funding

Ministerio de Ciencia, Tecnología e Innovación 80740-739-2020Universidad de Antioquia NAUniversidad Nacional de Colombia NA
6 · The paper itself

Abstract

This study presents the results obtained from extracting and quantifying cosmetically valuable metabolites such as phenolic compounds and mycosporine-like amino acids (MAAs) from 12 samples of marine macroalgae collected in the Colombian Caribbean Sea. Natural deep eutectic solvents (NADESs) were prepared, physicochemically tested (viscosity, surface tension, pH, and conductivity), and then compared with water as the reference solvent to quantify phenolic compounds using the Folin-Ciocalteau test. With a simple extraction assay with water and ultrasound followed by ultraviolet spectral scanning the presence of MAAs was easily determined in several of the analysed samples, and then they were identified by HPLC-DAD. Hydrochloric acid solution at 5% extracted a higher content of phenolic compounds than NADES and water. The NADES that showed the highest phenolic compound extraction yield was a mixture of betaine, glucose, and water with 1:1:5 molar ratio.

Indexed as

CosmeticsDeep Eutectic SolventsSeaweedAmino AcidsChromatography, High Pressure LiquidColombiaPhenolsSargassumSolventsAmino AcidsCosmeticsDeep Eutectic SolventsPhenolsSolventsgreen chemistrymacroalgaemarine natural productsNADESnatural cosmetics

Identifiers

PMID40559649
PMCPMC12194361

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.