Evidence map›Paper›PMID 40559646›Full record

ArticleMarine drugs2025

The Conopeptide αD-FrXXA, an Inhibitor of Voltage-Gated Potassium Channels.

Luis Martínez-Hernández, Estuardo López-Vera, Ximena C Rodriguez-Ruiz, Mónica A Ortíz-Arellano

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luis Martínez-HernándezPosgrado en Ciencias Biológicas, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Estuardo López-VeraLaboratorio de Toxinología Marina, Unidad Académica de Ecología y Biodiversidad Acuática, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0000-0002-8750-3633
Ximena C Rodriguez-RuizLaboratorio de Toxinología Marina, Unidad Académica de Ecología y Biodiversidad Acuática, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0009-0008-1104-6414
Mónica A Ortíz-ArellanoLaboratorio de Malacología, Facultad de Ciencias del Mar, Universidad Autónoma de Sinaloa, Mazatlán 82000, Mexico.

Funding

UNAM Institutional Budgets to the laboratory of Toxinología Marina 615
6 · The paper itself

Abstract

The conopeptide αD-FrXXA was previously isolated by our team from the venom of the vermivorous snail

Indexed as

ConotoxinsConus SnailPeptidesPotassium Channel BlockersPotassium Channels, Voltage-GatedAnimalsDose-Response Relationship, DrugOocytesPatch-Clamp TechniquesShaker Superfamily of Potassium ChannelsXenopus laevisConotoxinsPeptidesPotassium Channel BlockersPotassium Channels, Voltage-GatedShaker Superfamily of Potassium ChannelsconotoxinsConus fergusoniKv channelsαD-superfamily

Identifiers

PMID40559646
PMCPMC12194669

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.