Evidence map›Paper›PMID 40559612›Full record

ArticlePathogens (Basel, Switzerland)2025

CRISPR-Cas Dynamics in Carbapenem-Resistant and Carbapenem-Susceptible

Ivana Jurić, Marko Jelić, Manda Markanović, Lucija Kanižaj, Zrinka Bošnjak, Ana Budimir, Tomislav Kuliš, Arjana Tambić-Andrašević, Ivana Ivančić-Baće, Ivana Mareković

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Molecular Insights into Carbapenem Resistance inInternational journal of molecular sciences · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ivana JurićClinical Microbiology, Infection Prevention and Control Department, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
Marko JelićDepartment of Clinical Microbiology, University Hospital for Infectious Diseases "Fran Mihaljević", Mirogojska 8, 10000 Zagreb, Croatia.ORCID 0000-0002-3554-3668
Manda MarkanovićClinical Microbiology, Infection Prevention and Control Department, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
Lucija KanižajClinical Microbiology, Infection Prevention and Control Department, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
Zrinka BošnjakClinical Microbiology, Infection Prevention and Control Department, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
Ana BudimirClinical Microbiology, Infection Prevention and Control Department, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
Tomislav KulišDepartment of Urology, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.ORCID 0000-0002-0895-5691
Arjana Tambić-AndraševićDepartment of Clinical Microbiology, University Hospital for Infectious Diseases "Fran Mihaljević", Mirogojska 8, 10000 Zagreb, Croatia.ORCID 0000-0001-6232-1465
Ivana Ivančić-BaćeMolecular Biology Department, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.ORCID 0000-0003-2018-3150
Ivana MarekovićClinical Microbiology, Infection Prevention and Control Department, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.

Funding

School od Medicine, University of Zagreb and Faculty of Science, University of Zagreb 10106-24-1295 to I.M. and 20286539 to I.I.B.
6 · The paper itself

Abstract

(1) Background: CRISPR-Cas systems provide adaptive immunity against mobile genetic elements (MGEs) carrying antimicrobial resistance (AMR) genes. Carbapenem-resistant (CR)

Indexed as

Carbapenem-Resistant EnterobacteriaceaeCarbapenemsCRISPR-Cas SystemsKlebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCroatiaDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsMultilocus Sequence TypingTertiary Care CentersAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsantimicrobial resistancecarbapenemase genescarbapenem resistanceCRISPR-Cas systemCRISPR lociKlebsiella pneumoniaeMLSTPFGEsubtypes I-E and I-E*

Identifiers

PMID40559612
PMCPMC12195874

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.