Evidence map›Paper›PMID 40559596›Full record

Observational studyPathogens (Basel, Switzerland)2025

Characteristics of Neonates with Sepsis Associated with Antimicrobial Resistance and Mortality in a Tertiary Hospital in Mexico: A Retrospective Observational Study.

Uriel A Angulo-Zamudio, Maria Luisa Velazquez-Meza, Jesus J Martinez-Garcia, Nidia Leon-Sicairos, Jorge Velazquez-Roman, Hector Flores-Villaseñor, Claudia Leon-Sicairos, Francisco A Martínez-Villa, Adrian Canizalez-Roman

Abstract readObservational Study
In one paragraph

Observational study in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Uriel A Angulo-ZamudioSchool of Medicine, Autonomous University of Sinaloa, Culiacan 80019, Sinaloa, Mexico.ORCID 0000-0003-2733-0766
Maria Luisa Velazquez-MezaThe Women's Hospital, Secretariat of Health, Culiacan 80020, Sinaloa, Mexico.
Jesus J Martinez-GarciaSchool of Medicine, Autonomous University of Sinaloa, Culiacan 80019, Sinaloa, Mexico.ORCID 0000-0002-9555-262X
Nidia Leon-SicairosSchool of Medicine, Autonomous University of Sinaloa, Culiacan 80019, Sinaloa, Mexico.ORCID 0000-0003-1470-3383
Jorge Velazquez-RomanSchool of Medicine, Autonomous University of Sinaloa, Culiacan 80019, Sinaloa, Mexico.
Hector Flores-VillaseñorSchool of Medicine, Autonomous University of Sinaloa, Culiacan 80019, Sinaloa, Mexico.
Claudia Leon-SicairosRegional Graduate Program in Biotechnology, Faculty of Chemical and Biological Sciences, Autonomous University of Sinaloa, Culiacan 80000, Sinaloa, Mexico.ORCID 0000-0002-4175-5763
Francisco A Martínez-VillaUnidad de Medicina Familiar No. 21, Mexican Social Security Institute, La Cruz de Elota 82700, Sinaloa, Mexico.
Adrian Canizalez-RomanSchool of Medicine, Autonomous University of Sinaloa, Culiacan 80019, Sinaloa, Mexico.ORCID 0000-0001-8605-0639

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to determine the epidemiological, clinical, and laboratory characteristics of newborns with sepsis in northwestern Mexico, identify the microorganisms causing early- and late-onset sepsis, and assess antimicrobial resistance. Additionally, it sought to associate neonatal characteristics with antimicrobial resistance or mortality. A retrospective study was conducted from August 2021 to April 2023, during which 8382 neonatal clinical records were analyzed to collect epidemiological, clinical, and laboratory characteristics, as well as microorganisms isolated from neonates and their antimicrobial resistance profiles. Of these, 314 neonates with sepsis were included. The incidence of neonatal sepsis was 4% (314/8382), and the mortality was 12.7% (40/314); late-onset sepsis (65.3%) was more frequent than early-onset sepsis (34.7%).

Indexed as

Neonatal SepsisSepsisAnti-Bacterial AgentsFemaleHumansIncidenceInfant, NewbornMaleMexicoRetrospective StudiesTertiary Care CentersAnti-Bacterial Agentsantimicrobial resistancebiomarkersearly-onset sepsislate-onset sepsisneonatal sepsis

Identifiers

PMID40559596
PMCPMC12195758

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.