Evidence map›Paper›PMID 40559519›Full record

ArticlePathogens (Basel, Switzerland)2025

Broad Antifungal Spectrum of the Pore-Forming Peptide C14R Against

Carolina Firacative, Norida Vélez, Ann-Kathrin Kissmann, Daniel Alpízar-Pedraza, Jan-Christoph Walter, Ludger Ständker, Frank Rosenau

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolina FiracativeStudies in Translational Microbiology and Emerging Diseases (MICROS) Research Group, School of Medicine and Health Sciences, Universidad de Rosario, Bogota 111221, Colombia.ORCID 0000-0001-7547-5172
Norida VélezStudies in Translational Microbiology and Emerging Diseases (MICROS) Research Group, School of Medicine and Health Sciences, Universidad de Rosario, Bogota 111221, Colombia.
Ann-Kathrin KissmannInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-7164-0166
Daniel Alpízar-PedrazaInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-0281-680X
Jan-Christoph WalterInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.
Ludger StändkerCore Facility for Functional Peptidomics (CFP), Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-8436-4260
Frank RosenauInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-9297-6419

Funding

Alexander von Humboldt Foundation 1160914Austrian Research Promotion Agency 915477German Academic Exchange Service 57592717German Research Society 465229237 and 316249678Gesellschaft für Forschungsförderung FTI22-G-012
6 · The paper itself

Abstract

The World Health Organization (WHO) prioritized 19 fungal species based on the significant impact of these pathogens on human health, including the emergence of antifungal resistance, which highlights the necessity of finding new antifungal therapies. Among these novel therapeutic approaches, the antimicrobial pore-forming peptide C14R has shown to be promising against

Indexed as

Antifungal AgentsCandidaCryptococcusPore Forming Cytotoxic ProteinsDrug Resistance, FungalHumansMicrobial Sensitivity TestsWorld Health OrganizationAntifungal AgentsPore Forming Cytotoxic Proteinsantifungal resistanceantimicrobial peptidesC14RCandidacryptococcosisCryptococcusinvasive candidiasis

Identifiers

PMID40559519
PMCPMC12196350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.