Evidence map›Paper›PMID 40559446›Full record

ArticleMethods and protocols2025

Synthesis of DOTA-Based

Jason P Meier, Mohammed Bhuiyan, Richard Freifelder, Hannah J Zhang, Lucas Gonzalez, Antonino Pusateri, Hsiu-Ming Tsai, Lara Leoni, Kaustab Ghosh, Erica Markiewicz and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods and protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Emerging Theranostic Radiometals (Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jason P MeierDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-8188-5204
Mohammed BhuiyanDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.
Richard FreifelderDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.
Hannah J ZhangDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.
Lucas GonzalezDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.
Antonino PusateriDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-9660-3919
Hsiu-Ming TsaiIntegrated Small Animal Imaging Research Resource, Office of Shared Research Facilities, The University of Chicago, Chicago, IL 60637, USA.
Lara LeoniIntegrated Small Animal Imaging Research Resource, Office of Shared Research Facilities, The University of Chicago, Chicago, IL 60637, USA.
Kaustab GhoshDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-8477-6962
Erica MarkiewiczIntegrated Small Animal Imaging Research Resource, Office of Shared Research Facilities, The University of Chicago, Chicago, IL 60637, USA.
Christopher HenningDepartment of Medicine, The University of Chicago, Chicago, IL 60637, USA.
Yuhan ZhangDepartment of Medicine, The University of Chicago, Chicago, IL 60637, USA.
Ralph WeichselbaumUChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.
Jerry NolenUChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.ORCID 0000-0002-2160-0422
David A RotschUChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.ORCID 0000-0002-7184-9875
Chien-Min KaoDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-8785-5225
Russell Z SzmulewitzUChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.
Chin-Tu ChenDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.
Satish K ChitneniDepartment of Radiology, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-1183-2286

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI KUNLE ODUNSI · 1985 to 2026
$122.1M
Integrating Preclinical and Translational Imaging Resources for Animal ResearchS10OD025265 · OD · UNIVERSITY OF CHICAGO · PI CHEN, CHIN-TU · 2018 to 2018
$319k
National Institute of Health P30 CA14599NCI NIH HHS P30 CA014599NIH HHS S10 OD025265ODCDC CDC HHS S10 OD025265UChicago/Argonne Joint Radioisotope Initiative N/aUChicago Comprehensive Cancer Center UChicago High-Risk and Advanced Prostate Cancer (UCHAP) Team Science Research AwardUChicago Joint Task Force Initiative N/a
6 · The paper itself

Abstract

The implementation of theranostics in oncologic nuclear medicine has exhibited immense potential in improving patient outcomes in prostate cancer with the implementation of [

Indexed as

nuclear medicineoncologyprostate cancerPSMA-617radiochemistryScandium-43Scandium-44Scandium-47theranostics

Identifiers

PMID40559446
PMCPMC12196382

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.