ArticleMetabolites2025
Metabolomic Profiling Reveals PGPR-Driven Drought Tolerance in Contrasting
Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Application of Metabolomics in Defence Responses ofMetabolites · 2026Review
- Germination and Polishing Reshape Microbial Communities inJournal of agricultural and food chemistry · 2026Article
- Physiological Mechanisms of Plant Growth-Promoting Rhizobacteria in Enhancing Abiotic Stress Tolerance of Vegetable Crops: A Review.Plants (Basel, Switzerland) · 2026Review
- Rhizomicrobiomes from Drought-Adapted Mediterranean Species Differently Alter Leaf Metabolome ofPlants (Basel, Switzerland) · 2026Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundDrought stress is a major abiotic factor limiting
methodsMetabolite profiling was conducted using gas chromatography-mass spectrometry (GC-MS) to identify compounds that accumulated differentially across treatments. We applied multivariate statistical methods, such as Partial Least Squares Discriminant Analysis (PLS-DA), hierarchical clustering, and pathway enrichment analysis, to explore metabolic reprogramming.
resultsDrought stress induced significant changes in metabolite profile, particularly increasing the levels of osmoprotectants such as trehalose, glucose, sucrose, proline, and valine. Additionally, alterations in organic acids (malic acid and citric acid) and fatty acids (oleic acid and linoleic acid) were observed. PGPR inoculation further amplified these metabolic responses to enhance the osmotic regulation, reactive oxygen species (ROS) detoxification, and carbon-nitrogen metabolism, with RH-725 displaying a stronger adaptive response. Pathway enrichment analysis revealed that PGPR treatment significantly influenced metabolic pathways related to starch and sucrose metabolism, galactose metabolism, and amino acid biosynthesis, which play critical roles in drought adaptation.
conclusionThese findings provide insights into how PGPR contributes to stress resilience in
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