Evidence map›Paper›PMID 40559384›Full record

ArticleMetabolites2025

Oral Glucoraphanin and Curcumin Supplements Modulate Key Cytoprotective Enzymes in the Skin of Healthy Human Subjects: A Randomized Trial.

Anna L Chien, Hua Liu, Saleh Rachidi, Jessica L Feig, Ruizhi Wang, Kristina L Wade, Katherine K Stephenson, Aysegul Sevim Kecici, Jed W Fahey, Sewon Kang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Natural solutions for glowing skin: spices.Frontiers in nutrition · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anna L ChienDepartment of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Hua LiuDepartment of Pharmacology & Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0001-9141-5268
Saleh RachidiDepartment of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Jessica L FeigDepartment of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Ruizhi WangDepartment of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Kristina L WadeDepartment of Pharmacology & Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
Katherine K StephensonDepartment of Pharmacology & Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
Aysegul Sevim KeciciDepartment of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Jed W FaheyDepartment of Pharmacology & Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-2129-1834
Sewon KangDepartment of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

Funding

The Brassica Foundation for Chemoprotection Research 000The Cullman Chemoprotection Center 000The Lewis B. and Dorothy Cullman Foundation 000
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

broccolicancerclinicalerythemaphytochemicalsulforaphane

Identifiers

PMID40559384
PMCPMC12195189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.