Evidence map›Paper›PMID 40559374›Full record

ArticleMetabolites2025

Effect of Thermal Processing by Spray Drying on Key Ginger Compounds.

Alina Warren-Walker, Manfred Beckmann, Alison Watson, Steffan McAllister, Amanda J Lloyd

Abstract read
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alina Warren-WalkerDepartment of Life Sciences, Aberystwyth University, Aberystwyth, Wales SY23 3FL, UK.ORCID 0009-0007-7151-9503
Manfred BeckmannDepartment of Life Sciences, Aberystwyth University, Aberystwyth, Wales SY23 3FL, UK.
Alison WatsonDepartment of Life Sciences, Aberystwyth University, Aberystwyth, Wales SY23 3FL, UK.
Steffan McAllisterDepartment of Life Sciences, Aberystwyth University, Aberystwyth, Wales SY23 3FL, UK.
Amanda J LloydDepartment of Life Sciences, Aberystwyth University, Aberystwyth, Wales SY23 3FL, UK.ORCID 0000-0002-0775-3537

Funding

BBSRC BBSRC Biofortification Flexible Mobility Award (FMA)Innovate UK New Innovators in agri-tech & food technology, Mid & North Wales, Innovate UK, grant number 10133853
6 · The paper itself

Abstract

BACKGROUND/

objectivesSpray drying is a technique widely employed in the food and nutraceutical industries to convert liquid extracts into stable powders, preserving their functional properties. Ginger (

methodsFresh ginger juice was spray-dried using various carrier agents, including Clear Gum (CO03), pea protein, and inulin. Mass spectra of the resulting powders were acquired using High-Resolution Flow Infusion Electrospray Ionisation Mass Spectrometry (HR-FIE-MS) to obtain fingerprint data. Key bioactive compounds were tentatively identified to Level 2, and their relative intensities were assessed to evaluate the effects of different carriers on the chemical composition of the ginger powders.

resultsSpray drying with the commercial carrier CO03 resulted in an increase in shogaol analogues ([10]-, [8]-, and cis-[8]-shogaol), gingerenone B, and oxidation products such as 6-hydroxyshogaol, 6-dehydroshogaol, and zingerone. In contrast, natural carriers like pea protein and inulin led to lower relative intensities of these bioactives, suggesting limited capacity for promoting thermal transformations. Spray drying without a carrier produced a shogaol-dominant profile but resulted in powders with poor handling properties, such as stickiness and agglomeration. Antioxidant and total polyphenol assays showed that spray drying reduced antioxidant capacity, while total polyphenol content was more preserved; natural carriers such as inulin better maintained bioactivity compared to modified starch or pea protein.

conclusionsAmong the five formulations evaluated-ginger juice with no carrier, with CO03 (two dilutions), pea protein, or inulin-CO03-based samples showed the greatest chemical transformation, while inulin and pea protein better preserved antioxidant capacity but induced fewer metabolite changes. Thus, choice of carrier in the spray-drying process influences the chemical profile and functional characteristics of resultant ginger powders. While CO03 effectively enhances the formation of bioactive shogaols and related compounds, its ultra-processed nature may not align with clean-label product trends. Natural carriers, although more label-friendly, may not create the desired chemical transformations. Therefore, optimising carrier selection is important to balance bioactivity, product stability, and consumer acceptability in the development of ginger-based functional products.

Indexed as

bioactive compoundscarrier agentsfunctional foodsgingergingerolsmetabolomicsshogaolsspray dryingultra-processed

Identifiers

PMID40559374
PMCPMC12195494

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.