Evidence map›Paper›PMID 40559331›Full record

ArticleNeurology international2025

Effects of Motor Preparation on Walking Ability in Active Ankle Dorsiflexion.

Hiroki Ito, Hideaki Yamaguchi, Ryosuke Yamauchi, Ken Kitai, Kazuhei Nishimoto, Takayuki Kodama

Abstract read
In one paragraph

Article in Neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroki ItoGraduate School of Health Science, Kyoto Tachibana University, Yamashina-ku 607-8175, Kyoto, Japan.ORCID 0009-0005-3387-4438
Hideaki YamaguchiCARETECH Plus, Nagoya 462-0847, Aichi, Japan.
Ryosuke YamauchiGraduate School of Health Science, Kyoto Tachibana University, Yamashina-ku 607-8175, Kyoto, Japan.ORCID 0000-0003-3790-5439
Ken KitaiGraduate School of Health Science, Kyoto Tachibana University, Yamashina-ku 607-8175, Kyoto, Japan.
Kazuhei NishimotoGraduate School of Health Science, Kyoto Tachibana University, Yamashina-ku 607-8175, Kyoto, Japan.
Takayuki KodamaGraduate School of Health Science, Kyoto Tachibana University, Yamashina-ku 607-8175, Kyoto, Japan.ORCID 0000-0001-8784-6452

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThis study aimed to examine the influence of brain activity during motor preparation on walking ability, focusing on motor control during active ankle dorsiflexion.

methodsParticipants were classified into high- and low-corticomuscular coherence (CMC), an index of neuromuscular control based on the median value. Biomechanical and neurophysiological indices of active ankle dorsiflexion and walking ability were compared between the two groups. Additionally, a machine learning model was developed to accurately predict the CMC classification using brain neural activity during motor preparation.

resultsThe Cz-TA CMC (beta frequency band) during active ankle dorsiflexion successfully detected significant differences in the maximum dorsiflexion angle, inversion angular velocity, brain activity localization, and variations in Cz beta power values during the transition from motor preparation to execution. Furthermore, CMC identified significant differences in dorsiflexion angle changes after toe-off and inversion angles at initial contact during gait. A support-vector machine model predicting high or low CMC demonstrated high accuracy (Accuracy: 0.96, Precision: 0.92-1.00, Recall: 0.91-1.00, F1 Score: 0.95-0.96) during motor execution based on beta power values from -500 to 0 ms prior to the initiation of active ankle dorsiflexion (representing motor preparation).

conclusionsThese findings highlight that the motor preparation processes of the brain during active ankle dorsiflexion are involved in walking ability and can be used to predict it. This indicator is independent of disease severity and holds the potential to provide a clinically versatile evaluation method.

Indexed as

active ankle dorsiflexionbeta powercorticomuscular coherence (CMC)EEGLORETAmotor preparationsupport-vector machine (SVM)voluntary movement

Identifiers

PMID40559331
PMCPMC12196276

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.