Evidence map›Paper›PMID 40559257›Full record

ArticleNanomaterials (Basel, Switzerland)2025

Phenothiazine-Based Nanoaggregates: Dual Role in Bioimaging and Stem Cell-Driven Photodynamic Therapy.

Eleonora Calzoni, Alessio Cesaretti, Nicolò Montegiove, Maria Luisa Valicenti, Francesco Morena, Rajneesh Misra, Benedetta Carlotti, Sabata Martino

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Exploiting singlet fission inChemical science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eleonora CalzoniDepartment of Chemistry, Biology and Biotechnology, University of Perugia, 06100 Perugia, Italy.ORCID 0000-0002-2876-952X
Alessio CesarettiDepartment of Chemistry, Biology and Biotechnology, University of Perugia, 06100 Perugia, Italy.ORCID 0000-0001-5814-8524
Nicolò MontegioveDepartment of Civil and Environmental Engineering, University of Perugia, Via G. Duranti 93, 06125 Perugia, Italy.ORCID 0000-0002-0678-0824
Maria Luisa ValicentiDepartment of Chemistry, Biology and Biotechnology, University of Perugia, 06100 Perugia, Italy.
Francesco MorenaDepartment of Chemistry, Biology and Biotechnology, University of Perugia, 06100 Perugia, Italy.ORCID 0000-0001-9407-0576
Rajneesh MisraDepartment of Chemistry, Indian Institute of Technology Indore, Indore 453552, India.
Benedetta CarlottiDepartment of Chemistry, Biology and Biotechnology, University of Perugia, 06100 Perugia, Italy.ORCID 0000-0002-2980-2598
Sabata MartinoDepartment of Chemistry, Biology and Biotechnology, University of Perugia, 06100 Perugia, Italy.ORCID 0000-0002-3942-237X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotechnology is transforming contemporary medicine by providing cutting-edge tools for the treatment and diagnosis of complex disorders. Advanced techniques such as bioimaging and photodynamic therapy (PDT) combine early diagnosis and targeted therapy, offering a more precise approach than conventional treatments. However, a significant obstacle for PDT is the need to selectively deliver photosensitizers to disease sites while minimizing systemic side effects. In this context, mesenchymal stem cells have emerged as promising biological carriers due to their natural tropism towards tumors, low immunogenicity, and their ability to overcome biological barriers. In this study, two push-pull compounds,

Indexed as

aggregation-induced emissionbioimagingfluorescent probesmesenchymal stem cellsnanotechnologyphotodynamic therapyphotosensitizerspush–pull compoundstheranosticstumor-targeted delivery

Identifiers

PMID40559257
PMCPMC12196274

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.