Evidence map›Paper›PMID 40559235›Full record

Observational studyMedical sciences (Basel, Switzerland)2025

Confidential Audit of Perinatal Mortality in the Republic of Kazakhstan: A Pilot Study.

Aizada Marat, Zaituna Khamidullina, Svetlana Muratbekova, Kulyash Jaxalykova, Bekturgan Karin, Nazerke Samatova, Umit Usmanova, Madina Sharipova, Aknur Kobetayeva, Milan Terzic and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Medical sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aizada MaratDepartment of Obstetrics and Gynecology #1, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Zaituna KhamidullinaDepartment of Obstetrics and Gynecology #1, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Svetlana MuratbekovaHigher School of Medicine, NJSC Sh. Ualikhanov Kokshetau University, Kokshetau 020000, Kazakhstan.ORCID 0009-0001-1532-9584
Kulyash JaxalykovaDepartment of Neonatology, NJSC «Astana Medical University», Astana 010000, Kazakhstan.ORCID 0000-0001-5540-3331
Bekturgan KarinDepartment of Neonatology, NJSC «Astana Medical University», Astana 010000, Kazakhstan.
Nazerke SamatovaDepartment of Neonatology, NJSC «Astana Medical University», Astana 010000, Kazakhstan.ORCID 0009-0005-1548-8744
Umit UsmanovaDepartment of Neonatology, NJSC «Astana Medical University», Astana 010000, Kazakhstan.ORCID 0009-0000-1459-9809
Madina SharipovaDepartment of Obstetrics and Gynecology #1, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Aknur KobetayevaDepartment of Obstetrics and Gynecology #1, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Milan TerzicDepartment of Surgery, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0003-3914-5154
Yesbolat SakkoDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.
Gulzhanat AimagambetovaDepartment of Surgery, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0002-2868-4497

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPerinatal mortality is labeled as the loss of fetuses at or beyond 22 weeks of gestation, deaths during labor and delivery, as well as early neonatal deaths. Appropriate medical care provided in the perinatal period is an integral indicator of high-quality medical care. Although developed countries managed to decrease perinatal mortality, it remains high in the developing world. This study aims to perform a confidential audit of perinatal mortality (CAPM) across Kazakhstani maternity hospitals.

methodsA descriptive, observational cross-sectional study was conducted from January 2024 to December 2024. The structure of the underlying causes of mortality in the antenatal, intranatal, and early neonatal periods among different maternity hospitals of the Republic of Kazakhstan was analyzed.

resultsA total of 116 cases were assessed: 34 antenatal deaths, 6 intranatal, and 76 early neonatal. Most deaths occurred on the second day post-delivery. The analysis revealed that 93% of cases fell into categories indicating substandard or potentially inadequate care (categories 2 and 3). Intraventricular hemorrhage and sepsis emerged as leading causes of neonatal death. Among antenatal and intranatal deaths, significant proportions were associated with comorbid maternal conditions, insufficient antenatal visits, and inadequate perinatal support.

conclusionsCAPM proves to be a critical tool for identifying systemic gaps and guiding improvements in maternity services without attributing blame to health professionals. Findings underscore that many perinatal deaths could have been avoided with timely, evidence-based interventions across antenatal and neonatal care. Broader implementation and institutionalization of CAPM in Kazakhstan could lead to measurable reductions in perinatal mortality and improvements in maternal/newborn care outcomes. Factors such as preconception planning, improving the health of reproductive-age women, administration of folic acid, and reducing primary cesarean sections could assist in achieving the reduction in the perinatal mortality rate.

Indexed as

Perinatal MortalityAdultCross-Sectional StudiesFemaleHumansInfant, NewbornKazakhstanPerinatal DeathPilot ProjectsPregnancyantenatal mortalityconfidential auditintranatal mortalityKazakhstanneonatal mortalityperinatal mortalitystillbirth

Identifiers

PMID40559235
PMCPMC12194885

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.