Evidence map›Paper›PMID 40559228›Full record

ReviewMedical sciences (Basel, Switzerland)2025

Artificial Intelligence in the Histopathological Assessment of Non-Neoplastic Skin Disorders: A Narrative Review with Future Perspectives.

Mario Della Mura, Joana Sorino, Anna Colagrande, Maged Daruish, Giuseppe Ingravallo, Alessandro Massaro, Gerardo Cazzato, Carmelo Lupo, Nadia Casatta, Domenico Ribatti and 1 more

Abstract readReview
In one paragraph

Review in Medical sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Artificial intelligence-based quantification of epidermal proliferation and apoptosis in human skin.JID innovations : skin science from molecules to population health · 2026
    Article
  3. Diagnostic concordance of dermatopathology and PCR in differentiating eczema from psoriasis.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mario Della MuraSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0009-0009-5116-2484
Joana SorinoSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0009-0003-8458-8648
Anna ColagrandeSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-4676-0761
Maged DaruishDorset County Hospital NHS Foundation Trust, Dorchester DT1 2JY, UK.ORCID 0000-0001-9090-6380
Giuseppe IngravalloSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-4792-3545
Alessandro MassaroDepartment of Engineering, LUM-Libera Università Mediterranea "Giuseppe Degennaro", S.S. 100-Km-18, Parco il Baricentro, 70010 Bari, Italy.ORCID 0000-0003-1744-783X
Gerardo CazzatoSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-0325-4316
Carmelo LupoDepartment of Engineering and Applied Science, University of Bergamo, 24127 Bergamo, Italy.ORCID 0000-0003-3287-7299
Nadia CasattaDiapath SpA, 24057 Martinengo, Italy.ORCID 0000-0002-4861-0727
Domenico RibattiDepartment of Translational Biomedicine and Neuroscience, University of Bari Medical School, 70121 Bari, Italy.ORCID 0000-0003-4768-8431
Angelo VaccaCentro Interdisciplinare Ricerca Telemedicina-CITEL, Università degli Studi di Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-4567-8216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) is rapidly transforming diagnostic approaches in different fields of medical sciences, demonstrating an emerging potential to revolutionize dermatopathology due to its capacity to process large amounts of data in the shortest possible time, both for diagnosis and research purposes. Different AI models have been applied to neoplastic skin diseases, especially melanoma. However, to date, very few studies have investigated the role of AI in dermatoses. Herein, we provide an overview of the key aspects of AI and its functioning, focusing on medical applications. Then, we summarize all the existing English-language literature about AI applications in the field of non-neoplastic skin diseases: superficial perivascular dermatitis, psoriasis, fungal infections, onychomycosis, immunohistochemical characterization of inflammatory dermatoses, and differential diagnosis between the latter and mycosis fungoides (MF). Finally, we discuss the main challenges related to AI implementation in pathology.

Indexed as

Artificial IntelligenceSkin DiseasesDiagnosis, DifferentialHumansartificial intelligencedeep learningdermatopathologydigital pathologymachine learningskin pathology

Identifiers

PMID40559228
PMCPMC12195539

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.