Evidence map›Paper›PMID 40558980›Full record

ArticleInsects2025

Sec61s and Sec62/Sec63 Genes Are Essential for Survival by Regulating the Gut and Cuticle Development in

Xiaojian Liu, Mingzhu Ji, Jianzhen Zhang

Abstract read
In one paragraph

Article in Insects, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaojian LiuInstitute of Applied Biology, Shanxi University, Taiyuan 030006, China.ORCID 0000-0003-0160-7392
Mingzhu JiInstitute of Applied Biology, Shanxi University, Taiyuan 030006, China.
Jianzhen ZhangInstitute of Applied Biology, Shanxi University, Taiyuan 030006, China.

Funding

National Key R&D Program of China 2022YFD1700200National Natural Science Foundation of China 32472549Postgraduate Education Innovation Program of Shanxi Province 2024TD05
6 · The paper itself

Abstract

In eukaryotes, a lot of proteins are transported across the endoplasmic reticulum by the heterotrimeric Sec61 channel. And post-translational transport needs another Sec62/Sec63 complex. However, functions of these genes are poorly explored in insects. In this study, we first identified five Sec genes, named

Indexed as

cuticleintestinal tractLocusta migratoriaRNA interferenceSec61 channelSec62/Sec63 complex

Identifiers

PMID40558980
PMCPMC12192934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.