ReviewJournal of functional biomaterials2025
Antibacterial and Bactericidal Effects of the Er: YAG Laser on Oral Bacteria: A Systematic Review of Microbiological Evidence.
Review in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical Efficiency of Lasers in Endodontic Treatment of Primary Endodontic Cases: An Umbrella Review of Systematic Reviews.International dental journal · 2026Pooled it
- Efficacy of Er:YAG laser in removal of impacted mandibular third molars (a randomized controlled clinical trial).BMC oral health · 2026Trial
- Microbial Composition of Carious Dentin and the Impact of Minimally Invasive Excavation Techniques: A Narrative Review.International journal of molecular sciences · 2026Review
- Hypericin-Mediated Antimicrobial Photodynamic Therapy in Dentistry: A Systematic Review of Applications Against Oral Biofilms and Infections.Pharmaceutics · 2026Review
- Clinical Applications and Diagnostic Performance of Adjunctive Light-Based Optical Technologies in Oral Potentially Malignant Disorders and Squamous Cell Carcinoma: A Systematic Review.Journal of clinical medicine · 2026Review
- The antibacterial effect of chlorohexidine, Er:YAG laser and diode laser 980 nm as dental cavity disinfectants of dentine: an in vitro study.European journal of medical research · 2025Article
- Er:YAG Laser Energy Optimization for Reducing Single-Species Microbial Growth on Agar Surfaces In Vitro.Pathogens (Basel, Switzerland) · 2025Article
- Laser Interventions for Intraoral Halitosis: A Systematic Review of Randomized Controlled Trials.Pharmaceutics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Er:YAG laser has gained attention in dentistry for its potential to enhance microbial disinfection through targeted photothermal and photoacoustic mechanisms.
objectiveThis systematic review aimed to evaluate the antibacterial and bactericidal efficacy of Er:YAG laser therapy across clinically relevant oral pathogens in in vitro models.
methodsFollowing the PRISMA 2020 guidelines, a systematic search of PubMed, Embase, Scopus, and the Cochrane Library was conducted for studies published between 2015 and 2025. The review protocol was registered with PROSPERO (CRD420251031368). Eligibility criteria included in vitro or animal studies assessing the bactericidal effects of the Er:YAG laser on oral bacteria or fungi, either alone or in combination with chemical disinfectants. Study selection, data extraction, and quality assessment were conducted independently by multiple reviewers.
resultsTen in vitro studies met inclusion criteria. The Er:YAG laser demonstrated significant antibacterial effects against
conclusionsEr:YAG laser therapy is a promising adjunctive tool for microbial disinfection in dentistry, particularly in challenging anatomical sites. Further well-designed in vivo and clinical studies are needed to confirm its efficacy and determine optimal treatment parameters.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.