Evidence map›Paper›PMID 40558731›Full record

ReviewGels (Basel, Switzerland)2025

Alginate Sphere-Based Soft Actuators.

Umme Salma Khanam, Hyeon Teak Jeong, Rahim Mutlu, Shazed Aziz

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Umme Salma KhanamSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.ORCID 0000-0003-0520-2413
Hyeon Teak JeongDivision of Energy Engineering, Daejin University, Pocheon 11159, Republic of Korea.ORCID 0000-0002-5771-5416
Rahim MutluFaculty of Science and Engineering, Southern Cross University, Lismore, NSW 2480, Australia.ORCID 0000-0001-5576-8744
Shazed AzizSchool of Chemical Engineering, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-8834-0397

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alginate hydrogels offer distinct advantages as ionically crosslinked, biocompatible networks that can be shaped into spherical beads with high compositional flexibility. These spherical architectures provide isotropic geometry, modularity and the capacity for encapsulation, making them ideal platforms for scalable, stimuli-responsive actuation. Their ability to respond to thermal, magnetic, electrical, optical and chemical stimuli has enabled applications in targeted delivery, artificial muscles, microrobotics and environmental interfaces. This review examines recent advances in alginate sphere-based actuators, focusing on fabrication methods such as droplet microfluidics, coaxial flow and functional surface patterning, and strategies for introducing multi-stimuli responsiveness using smart polymers, nanoparticles and biologically active components. Actuation behaviours are understood and correlated with physical mechanisms including swelling kinetics, photothermal effects and the field-induced torque, supported by analytical and multiphysics models. Their demonstrated functionalities include shape transformation, locomotion and mechano-optical feedback. The review concludes with an outlook on the existing limitations, such as the material stability, cyclic durability and integration complexity, and proposes future directions toward the development of autonomous, multifunctional soft systems.

Indexed as

alginatehydrogel spheresmart materialssoft actuatorsstimuli-responsive polymers

Identifiers

PMID40558731
PMCPMC12192248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.