Evidence map›Paper›PMID 40558726›Full record

ArticleGels (Basel, Switzerland)2025

Gelatin/Cerium-Doped Bioactive Glass Composites for Enhancing Cellular Functions of Human Mesenchymal Stem Cells (hBMSCs).

Andrey Iodchik, Gigliola Lusvardi, Alfonso Zambon, Poh Soo Lee, Hans-Peter Wiesmann, Anne Bernhardt, Vera Hintze

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrey IodchikInstitute of Materials Science, Max Bergmann Center of Biomaterials, TU Dresden University of Technology, Budapester Str. 27, D-01069 Dresden, Germany.ORCID 0009-0009-6481-0233
Gigliola LusvardiDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-0772-6037
Alfonso ZambonDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-8074-2308
Poh Soo LeeInstitute of Materials Science, Max Bergmann Center of Biomaterials, TU Dresden University of Technology, Budapester Str. 27, D-01069 Dresden, Germany.ORCID 0000-0003-2285-3621
Hans-Peter WiesmannInstitute of Materials Science, Max Bergmann Center of Biomaterials, TU Dresden University of Technology, Budapester Str. 27, D-01069 Dresden, Germany.
Anne BernhardtCentre for Translational Bone, Joint and Soft Tissue Research, University Hospital "Carl Gustav Carus", TU Dresden University of Technology, Fetscherstraße 74, D-01307 Dresden, Germany.ORCID 0000-0002-1903-1929
Vera HintzeInstitute of Materials Science, Max Bergmann Center of Biomaterials, TU Dresden University of Technology, Budapester Str. 27, D-01069 Dresden, Germany.ORCID 0000-0002-5611-9903

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delayed or non-healing of bone defects in an aging, multi-morbid population is still a medical challenge. Current replacement materials, like autografts, are limited. Thus, artificial substitutes from biodegradable polymers and bioactive glasses (BGs) are promising alternatives. Here, novel cerium-doped mesoporous BG microparticles (Ce-MBGs) with different cerium content were included in photocrosslinkable, methacrylated gelatin (GelMA) for promoting cellular functions of human mesenchymal stem cells (hBMSCs). The composites were studied for intrinsic morphology and Ce-MBGs distribution by scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). They were gravimetrically analyzed for swelling and stability, compressive modulus via Microsquisher

Indexed as

cerium-doped mesoporous bioactive glasseshuman mesenchymal stem cellshydrogelsmethacrylated gelatinosteogenic differentiation

Identifiers

PMID40558726
PMCPMC12192449

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.