Evidence map›Paper›PMID 40558725›Full record

ArticleGels (Basel, Switzerland)2025

Zinc Alginate Hydrogel-Coated Wound Dressings: Fabrication, Characterization, and Evaluation of Anti-Infective and In Vivo Performance.

Adelina-Gabriela Niculescu, Alexandra Cătălina Bîrcă, George Dan Mogoşanu, Marius Rădulescu, Alina Maria Holban, Daniela Manuc, Adina Alberts, Alexandru Mihai Grumezescu, Laurenţiu Mogoantă

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adelina-Gabriela NiculescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0001-8968-504X
Alexandra Cătălina BîrcăDepartment of Science and Engineering of Oxide Materials and Nanomaterials, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.
George Dan MogoşanuDepartment of Pharmacognosy and Phytotherapy, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2 Petru Rareş Street, 200349 Craiova, Romania.ORCID 0000-0001-6338-9277
Marius RădulescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.
Alina Maria HolbanDepartment of Microbiology, Faculty of Biology, University of Bucharest, 91-95 Independenţei Avenue, 050095 Bucharest, Romania.
Daniela ManucCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-9320-8430
Adina AlbertsCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Alexandru Mihai GrumezescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0003-3036-094X
Laurenţiu MogoantăResearch Center for Microscopic Morphology and Immunology, University of Medicine and Pharmacy of Craiova, 2 Petru Rareş Street, 200349 Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The delayed healing and infection risks associated with chronic wounds and burns pose significant clinical challenges. Traditional dressings provide basic coverage but lack the bioactive properties needed for tissue regeneration and antimicrobial protection. In this study, we developed zinc alginate hydrogel-coated traditional wound dressings (WD@AlgZn) and evaluated their physicochemical properties, antimicrobial performance, and in vivo healing efficacy. Scanning electron microscopy (SEM) revealed a uniform coating of the zinc alginate network on dressing fibers, while Fourier-transform infrared spectroscopy (FT-IR) confirmed the successful incorporation of zinc ions. Antimicrobial assays further demonstrated that WD@AlgZn reduced bacterial loads (CFU/mL counts) by several orders of magnitude for both

Indexed as

antimicrobial propertiesbioactive wound dressingsburn wound treatmentfibroblast proliferationwound healingzinc alginate

Identifiers

PMID40558725
PMCPMC12191814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.