ArticleGels (Basel, Switzerland)2025
Performance Characterization and Antibacterial Activity of a Composite Hydrogel Composed of Oxidized κ-Carrageenan, Acrylamide, and Silver-Based Metal-Organic Frameworks.
Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
To advance seaweed polysaccharide applications in hydrogel wound dressings, five antibacterial composite hydrogels (groups A~E) were synthesized using oxidized κ-carrageenan (OKC), acrylamide (AM), and progressively increasing concentrations of silver-based metal-organic frameworks (Ag-MOFs). Systematic characterization revealed concentration-dependent effects: (1) positive correlations were obtained for the moisture content (MC, maximized at 82.70% in E) and antibacterial efficacy (dose-dependent enhancement); (2) negative impacts were obtained for the swelling ratio (SR, E: 479% vs. A: 808%); and (3) high-dose drawbacks but low-dose benefits in terms of water resistance (WR), tensile strength (TS), elongation at break (EB), and microstructure were obtained. Group B demonstrated optimal Ag-MOFs loading, enhancing TS and EB, while excessive Ag-MOFs loading in C~E significantly degraded them (
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