Evidence map›Paper›PMID 40558700›Full record

ArticleGels (Basel, Switzerland)2025

Effect of Calcination Temperature and Strontium Addition on the Properties of Sol-Gelled Bioactive Glass Powder.

Pei-Jung Chang, Jia-Yu Chen, Chi-Han Cheng, Kazuhiro Aoki, Cherng-Yuh Su, Chung-Kwei Lin

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pei-Jung ChangGraduate Institute of Manufacturing Technology, National Taipei University of Technology, Taipei 106, Taiwan.ORCID 0009-0003-5935-9130
Jia-Yu ChenSchool of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Chi-Han ChengSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Kazuhiro AokiDepartment of Basic Oral Health Engineering, Graduate School, Institute of Science Tokyo, Tokyo 113-8549, Japan.ORCID 0000-0001-6643-6315
Cherng-Yuh SuGraduate Institute of Manufacturing Technology, National Taipei University of Technology, Taipei 106, Taiwan.ORCID 0000-0001-5684-5588
Chung-Kwei LinResearch Center of Digital Oral Science and Technology, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0003-4964-8687

Funding

National Science and Technology Council NSTC 113-2622-E-038-002National Science and Technology Council NSTC 113-2813-C-038-017-E
6 · The paper itself

Abstract

Strontium-added bioactive glass (SBG) has been widely used in bone tissue engineering. SBG can be prepared by conventional high-temperature melt-quenching or calcining sol-gelled powder at 700 °C or above. In the present study, the effects of calcination temperature (400-650 °C) and the amount of strontium addition (0-7 mol.%) were investigated simultaneously. The sol-gel process and post-calcination were used to prepare the Sr-added 58S bioactive glass (SBG) powders. The bioactivity of the SBG powder was assessed by immersing it in simulated body fluid, while biocompatibility and cytotoxicity were evaluated using L929 and MG63 cells, and a zebrafish animal model. The calcination temperatures were determined by thermogravimetric analysis based on the weight loss at various stages. X-ray diffraction was used to reveal the crystalline structure of calcined or SBF-immersed SBG powders. Meanwhile, the texture characteristics of SBG powders were examined by the BET method. Fourier-transformed infrared spectroscopy and scanning electron microscopy were used to investigate the absorption bands and powder morphology of SBG powders before and after SBF immersion. The experimental results showed that all SBG powders were mesoporous with a high specific surface area larger than 200 m

Indexed as

bioactive glassbiocompatibilitycalcinationcytotoxicityhydroxyapatitemineralizationsol gelstrontium

Identifiers

PMID40558700
PMCPMC12191557

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.