Evidence map›Paper›PMID 40558559›Full record

ArticleCells2025

Cytokinesis in Suspension: A Distinctive Trait of Mesenchymal Stem Cells.

Bhavna Rani, Hong Qian, Staffan Johansson

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bhavna RaniDepartment of Medical Biochemistry and Microbiology (IMBIM), Biomedical Center, Uppsala University, P.O. Box 582, 751 23 Uppsala, Sweden.ORCID 0000-0002-2299-1453
Hong QianDepartment of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institute, Karolinska University Hospital, 141 86 Stockholm, Sweden.ORCID 0000-0002-2512-9199
Staffan JohanssonDepartment of Medical Biochemistry and Microbiology (IMBIM), Biomedical Center, Uppsala University, P.O. Box 582, 751 23 Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) have a broad clinical potential, but their selection and expansion on plastic cause unknown purity and phenotypic alterations, reducing therapy efficiency. Furthermore, their behavior in non-adherent conditions during systemic transplantation remains poorly understood. The sphere formation from single cells is commonly used to assess stemness, but MSCs lack this ability, raising questions about their anchorage dependence for proliferation. We investigated whether bone marrow-derived MSCs can complete cytokinesis in non-adherent environments. Primary

Indexed as

CytokinesisMesenchymal Stem CellsAnimalsCell AdhesionCell ProliferationCells, CulturedHumansMiceNocodazoleNocodazoleALIXanchorage independencecytokinesismidbodyMSC

Identifiers

PMID40558559
PMCPMC12191188

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.