Evidence map›Paper›PMID 40558517›Full record

ArticleCells2025

Adenosine A

Ignacio Arias, Claudia Jara, Pablo Mendoza-Soto, Yessica Nahuelpán, Claudio Cappelli, Carlos Oyarzún, Diego Carrillo-Beltrán, Claudia Quezada-Monrás, Angelo Torres-Arévalo, Rody San Martín

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ignacio AriasMolecular Pathology Laboratory, Institute of Biochemistry and Microbiology, Science Faculty, Universidad Austral de Chile, Valdivia 5110566, Chile.
Claudia JaraMolecular Pathology Laboratory, Institute of Biochemistry and Microbiology, Science Faculty, Universidad Austral de Chile, Valdivia 5110566, Chile.
Pablo Mendoza-SotoMolecular Pathology Laboratory, Institute of Biochemistry and Microbiology, Science Faculty, Universidad Austral de Chile, Valdivia 5110566, Chile.ORCID 0009-0008-3624-3457
Yessica NahuelpánMolecular Pathology Laboratory, Institute of Biochemistry and Microbiology, Science Faculty, Universidad Austral de Chile, Valdivia 5110566, Chile.
Claudio CappelliMolecular Pathology Laboratory, Institute of Biochemistry and Microbiology, Science Faculty, Universidad Austral de Chile, Valdivia 5110566, Chile.ORCID 0000-0002-3492-4725
Carlos OyarzúnMolecular Pathology Laboratory, Institute of Biochemistry and Microbiology, Science Faculty, Universidad Austral de Chile, Valdivia 5110566, Chile.
Diego Carrillo-BeltránTumor Biology Laboratory, Institute of Biochemistry and Microbiology, Science Faculty, Universidad Austral de Chile, Valdivia 5110566, Chile.
Claudia Quezada-MonrásTumor Biology Laboratory, Institute of Biochemistry and Microbiology, Science Faculty, Universidad Austral de Chile, Valdivia 5110566, Chile.
Angelo Torres-ArévaloEscuela de Medicina Veterinaria, Facultad de Medicina Veterinaria y Recursos Naturales, Sede Talca, Universidad Santo Tomás, Talca 3473620, Chile.ORCID 0009-0009-8956-6724
Rody San MartínMolecular Pathology Laboratory, Institute of Biochemistry and Microbiology, Science Faculty, Universidad Austral de Chile, Valdivia 5110566, Chile.

Funding

Agencia Nacional de Investigación y Desarrollo 1171340, 1211613, 1241275, 11230660
6 · The paper itself

Abstract

Studies have emphasized alleviating fibrogenesis through interference with adenosine signaling in experimental diabetic nephropathy. We found that the in vivo antagonism of the adenosine A

Indexed as

Adenosine A2 Receptor AntagonistsDiabetes Mellitus, ExperimentalDiabetic NephropathiesPodocytesReceptor, Adenosine A2BSignal TransductionSmad2 ProteinSmad3 ProteinTranscription Factor RelATransforming Growth Factor betaAnimalsHumansMaleNF-kappa BPhenotypeRatsAdenosine A2 Receptor AntagonistsNF-kappa BReceptor, Adenosine A2BSmad2 ProteinSmad3 ProteinTranscription Factor RelATransforming Growth Factor betaadenosine receptorsdiabetic nephropathyglomerulosclerosisTGF-beta 1

Identifiers

PMID40558517
PMCPMC12190782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.