Evidence map›Paper›PMID 40558461›Full record

SynthesisBiosensors2025

The Use of CRISPR-Cas Systems for Viral Detection: A Bibliometric Analysis and Systematic Review.

Othmane Jeddoub, Nadia Touil, Omar Nyabi, Elmostafa El Fahime, Khalid Ennibi, Jean-Luc Gala, Abdelaziz Benjouad, Lamiae Belayachi

Abstract readSystematic Review
In one paragraph

Synthesis in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Othmane JeddoubInternational Faculty of Medicine, Health Sciences Research Center, College of Health Sciences, International University of Rabat, Technopolis Parc, Rocade of Rabat-Salé, Sala-Al Jadida 11100, Morocco.ORCID 0009-0003-2754-290X
Nadia TouilUnité de Recherche Biomédicale et Epidemiologie (URBE), Centre de Virologie, Maladies Infectieuses et Tropicales, Hopital Militaire d'Instruction Mohammed V, Faculté de Médecine et de Pharmacie de Rabat, Rabat 10100, Morocco.ORCID 0000-0003-4183-7758
Omar NyabiCenter for Applied Molecular Technologies (CTMA), Institute of Clinical and Experimental Research, Université Catholique de Louvain, 1200 Brussels, Belgium.ORCID 0000-0003-0479-4103
Elmostafa El FahimeMohammed VI Center for Research and Innovation (CM6RI), Rabat 10100, Morocco.ORCID 0000-0001-7812-0641
Khalid EnnibiUnité de Recherche Biomédicale et Epidemiologie (URBE), Centre de Virologie, Maladies Infectieuses et Tropicales, Hopital Militaire d'Instruction Mohammed V, Faculté de Médecine et de Pharmacie de Rabat, Rabat 10100, Morocco.
Jean-Luc GalaCenter for Applied Molecular Technologies (CTMA), Institute of Clinical and Experimental Research, Université Catholique de Louvain, 1200 Brussels, Belgium.ORCID 0000-0002-7749-573X
Abdelaziz BenjouadInternational Faculty of Medicine, Health Sciences Research Center, College of Health Sciences, International University of Rabat, Technopolis Parc, Rocade of Rabat-Salé, Sala-Al Jadida 11100, Morocco.ORCID 0000-0002-0459-4219
Lamiae BelayachiInternational Faculty of Medicine, Health Sciences Research Center, College of Health Sciences, International University of Rabat, Technopolis Parc, Rocade of Rabat-Salé, Sala-Al Jadida 11100, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral infections impose a significant burden on global public health and the economy. This study examines the current state of CRISPR-Cas system research, focusing on their applications in viral detection and their evolution over recent years. A bibliometric analysis and systematic review were conducted using articles published between 2019 and 2024, retrieved from Web of Science, Scopus, and PubMed databases. Out of 2713 identified articles, 194 were included in the analysis. The findings reveal substantial growth in scientific output related to CRISPR-Cas systems, with the United States leading in research and development in this field. The rapid increase in CRISPR-Cas research during this period underscores its immense potential to transform viral diagnostics. With advantages such as speed, precision, and suitability for deployment in resource-limited settings, CRISPR-Cas systems outperform many traditional diagnostic methods. The concerted efforts of scientists worldwide further highlight the promising future of this technology. CRISPR-Cas systems are emerging as a powerful alternative, offering the possibility of expedited and accessible point-of-care testing and paving the way for more equitable and effective diagnostics on a global scale.

Indexed as

CRISPR-Cas SystemsVirus DiseasesVirusesBibliometricsHumansbibliometric analysisCRISPR-Cas systemsisothermal amplificationviral diagnostic assay

Identifiers

PMID40558461
PMCPMC12190998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.