A Metal-Organic Hybrid Composed of Dual Quenching Cofactors as a Nanoquencher for the Fluorescent Determination of Protease Caspase-3.

Fengli Gao, Lin Liu, Cancan He, Yong Chang, Weiqiang Wang

Abstract read

In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fengli GaoHenan Province Key Laboratory of New Opto-electronic Functional Materials, College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.

Lin LiuHenan Province Key Laboratory of New Opto-electronic Functional Materials, College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.ORCID 0000-0001-7982-6005

Cancan HeHenan Province Key Laboratory of New Opto-electronic Functional Materials, College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.

Yong ChangHenan Province Key Laboratory of New Opto-electronic Functional Materials, College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.ORCID 0000-0001-7807-9730

Weiqiang WangInternational Joint Laboratory of Henan Photoelectric Functional Materials, College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China.

Funding

Program for Innovative Research Team of Science and Technology in Anyang Normal University 2023AYSYKYCXTD02Science & Technology Foundation of Henan Province 242102310362

6 · The paper itself

Abstract

Nanoquenchers with a single quenching cofactor exhibit limited fluorescence quenching efficiency. In this work, a metal-organic hybrid with dual quenching cofactors (Cu

Indexed as

Biosensing TechniquesCaspase 3CopperFluorescenceFluorescent DyesHumansSpectrometry, FluorescenceCaspase 3CopperFluorescent Dyesapoptosiscaspase-3metal–organic hybridnanoquencherprotease

Identifiers

PMID40558436

DOI10.3390/bios15060354

PMCPMC12190246

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.