Evidence map›Paper›PMID 40558378›Full record

ArticleBiomimetics (Basel, Switzerland)2025

Chemical and Biological Properties of C-Point Obturation Cones.

Marina Angélica Marciano, Paulo Jorge Palma, Ana Cristina Padilha Janini, Brenda Fornazaro Moraes, Thiago Bessa Marconato Antunes, Ribamar Lazanha Lucateli, Bruno Martini Guimarães, Mariza Akemi Matsumoto, Diana Bela Sequeira, Talita Tartari and 2 more

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marina Angélica MarcianoDepartment of Restorative Dentistry-Endondontic, School of Dentistry of Piracicaba, State University of Campinas, São Paulo 13414-903, Brazil.
Paulo Jorge PalmaInstitute of Endodontics, Faculty of Medicine, University of Coimbra, Coimbra, Portugal and Center for Innovation and Research in Oral Sciences (CIROS), 3000-075 Coimbra, Portugal.ORCID 0000-0003-4730-8072
Ana Cristina Padilha JaniniDepartment of Restorative Dentistry-Endondontic, School of Dentistry of Piracicaba, State University of Campinas, São Paulo 13414-903, Brazil.
Brenda Fornazaro MoraesDepartment of Restorative Dentistry-Endondontic, School of Dentistry of Piracicaba, State University of Campinas, São Paulo 13414-903, Brazil.ORCID 0009-0008-6995-3930
Thiago Bessa Marconato AntunesDepartment of Restorative Dentistry-Endondontic, School of Dentistry of Piracicaba, State University of Campinas, São Paulo 13414-903, Brazil.
Ribamar Lazanha LucateliDepartment of Surgery, Dental School of Ribeirão Preto, University of São Paulo-USP, Ribeirão Preto, São Paulo 14040-900, Brazil.
Bruno Martini GuimarãesSchool of Dentistry, Federal University of Alfenas, Alfenas 37130-001, Brazil.ORCID 0000-0002-8604-4180
Mariza Akemi MatsumotoDepartment of Basic Sciences, Dental School of Araçatuba, State University of São Paulo, São Paulo 16015-050, Brazil.ORCID 0000-0001-5389-0105
Diana Bela SequeiraCNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Talita TartariDepartment of Restorative Dentistry-Endondontic, School of Dentistry of Piracicaba, State University of Campinas, São Paulo 13414-903, Brazil.ORCID 0000-0003-4372-0158
Brenda Paula Figueiredo Almeida GomesDepartment of Restorative Dentistry-Endondontic, School of Dentistry of Piracicaba, State University of Campinas, São Paulo 13414-903, Brazil.
Marco Antonio Hungaro DuarteDepartment of Dentistry, Endodontics and Dental Materials, Dental School of Bauru, University of São Paulo-USP, São Paulo 17012-901, Brazil.ORCID 0000-0003-3051-737X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the chemical composition and subcutaneous tissue biocompatibility of C-Point, a root canal filling material, compared to ProTaper gutta-percha cones (control). Material characterization was conducted using scanning electron microscopy with energy-dispersive spectroscopy (SEM-EDS). For biocompatibility assessment, both materials were implanted subcutaneously in the dorsal connective tissue of sixteen albino rats (n = 8 per group). Histological evaluation of inflammatory infiltrate intensity was performed at 30 and 60 days post-implantation, with statistical analysis (significance set at

Indexed as

biocompatibilitybiomaterialsmaterials scienceroot canal filling

Identifiers

PMID40558378
PMCPMC12190228

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.