ArticleCurrent oncology (Toronto, Ont.)2025
Design and Development of a Device (Sifilotto
Silvana Parisi, Giacomo Ferrantelli, Anna Santacaterina, Elvio Grazioso Russi, Federico Chillari, Claudio Napoli, Anna Brogna, Carmelo Siragusa, Miriam Sciacca, Antonio Pontoriero and 2 more
Abstract readEvaluation Study
In one paragraphArticle in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Silvana ParisiDepartment of Biomedical Dental and Morphological and Functional Imaging (BIOMORF), Residency School of Radiation Oncology, University of Messina, Via Consolare Valeria 1, 98124 Messina, Italy.
Giacomo FerrantelliDepartment of Biomedical Dental and Morphological and Functional Imaging (BIOMORF), Residency School of Radiation Oncology, University of Messina, Via Consolare Valeria 1, 98124 Messina, Italy.ORCID 0000-0001-7221-2369 Anna SantacaterinaDepartment of Biomedical Dental and Morphological and Functional Imaging (BIOMORF), Residency School of Radiation Oncology, University of Messina, Via Consolare Valeria 1, 98124 Messina, Italy.
Elvio Grazioso RussiDepartment of Biomedical Dental and Morphological and Functional Imaging (BIOMORF), Residency School of Radiation Oncology, University of Messina, Via Consolare Valeria 1, 98124 Messina, Italy.ORCID 0000-0003-1278-2313 Federico ChillariRadiotherapy Unit, "Villa Santa Teresa Diagnostica Per Immagini e Radioterapia", Viale Ing. G. Bagnera 14, 90011 Bagheria, Italy.
Claudio NapoliDepartment of Biomedical Dental and Morphological and Functional Imaging (BIOMORF), Residency School of Radiation Oncology, University of Messina, Via Consolare Valeria 1, 98124 Messina, Italy.
Anna Brogna"D.A.I Servizi" Department, COU Medical Physics, University Hospital "AOU G. Martino", Via Consolare Valeria 1, 98124 Messina, Italy.
Carmelo Siragusa"D.A.I Servizi" Department, COU Medical Physics, University Hospital "AOU G. Martino", Via Consolare Valeria 1, 98124 Messina, Italy.
Miriam SciaccaDepartment of Biomedical Dental and Morphological and Functional Imaging (BIOMORF), Residency School of Radiation Oncology, University of Messina, Via Consolare Valeria 1, 98124 Messina, Italy.ORCID 0009-0005-1165-8494 Antonio PontorieroDepartment of Biomedical Dental and Morphological and Functional Imaging (BIOMORF), Residency School of Radiation Oncology, University of Messina, Via Consolare Valeria 1, 98124 Messina, Italy.ORCID 0000-0003-3011-6779 Giuseppe IatìDepartment of Biomedical Dental and Morphological and Functional Imaging (BIOMORF), Residency School of Radiation Oncology, University of Messina, Via Consolare Valeria 1, 98124 Messina, Italy.ORCID 0000-0001-6287-2806 Stefano PergolizziDepartment of Biomedical Dental and Morphological and Functional Imaging (BIOMORF), Residency School of Radiation Oncology, University of Messina, Via Consolare Valeria 1, 98124 Messina, Italy.ORCID 0000-0002-4696-7634 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Standard of Care (SOC) for locally advanced cervical cancer is represented by external beam radiation therapy concurrent with platinum-based chemotherapy and immunotherapy (cCIRT) followed by brachytherapy boost and immunotherapy maintenance. In some instances, it is impossible to perform brachytherapy due to patient and/or cancer issues. In these circumstances, an external beam boost could be delivered. Using a robotic arm LINAC, it is mandatory to use intramucosal implanted fiducials which are needed for tumour tracking. To avoid invasive procedures, we developed an original intravaginal 3D-printed universal device containing gold fiducials embedded within it. In this paper, we describe the step-by-step procedure that allowed us to obtain the utility model patent, including the in vivo test (feasibility, reproducibility, device compliance) on seven patients within the study protocol "STereotActic Radiotherapy Boost in locally Advanced Cervical carcinoma patientS" (STARBACS).
Indexed as
Carcinoma, Squamous CellRadiosurgeryRobotic Surgical ProceduresStereotaxic TechniquesUterine Cervical NeoplasmsClinical Trials as TopicEquipment DesignFeasibility StudiesFemaleFiducial MarkersHumansPrinting, Three-DimensionalReproducibility of ResultsTreatment OutcomeVaginabrachytherapycervical cancerendovaginal applicatorlocally advancedrobotic LINACstereotactic
Identifiers
PMID40558297
PMCPMC12191586
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