Evidence map›Paper›PMID 40558295›Full record

ArticleCurrent oncology (Toronto, Ont.)2025

Mucinous Cystic Neoplasms in Male Patients: Histopathological and Molecular Diagnoses.

Lara Malaspina, Natale Calomino, Ludovico Carbone, Anastasia Batsikosta, Fabiola Rossi, Gianmario Edoardo Poto, Aurora Visani, Lucia Mundo, Bina Barbato, Ilaria Monteleone and 2 more

Abstract readCase Reports
In one paragraph

Article in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lara MalaspinaPathology Unit, Ospedale Civico di Carrara, 54033 Carrara, Italy.
Natale CalominoUnit of General Surgery and Kidney Transplantation, Department of Surgery, Siena University Hospital, 53100 Siena, Italy.ORCID 0000-0001-5426-5985
Ludovico CarboneUnit of Surgical Oncology, Department of Medicine Surgery and Neurosciences, Siena University Hospital, 53100 Siena, Italy.ORCID 0000-0003-2862-6788
Anastasia BatsikostaPathological Anatomy Unit, Department of Medical Biotechnology, Siena University Hospital, 53100 Siena, Italy.
Fabiola RossiPathology Unit, Ospedale Misericordia di Grosseto, 58100 Grosseto, Italy.
Gianmario Edoardo PotoUnit of Surgical Oncology, Department of Medicine Surgery and Neurosciences, Siena University Hospital, 53100 Siena, Italy.ORCID 0000-0001-8515-2414
Aurora VisaniUnit of Surgical Oncology, Department of Medicine Surgery and Neurosciences, Siena University Hospital, 53100 Siena, Italy.
Lucia MundoPathological Anatomy Unit, Department of Medical Biotechnology, Siena University Hospital, 53100 Siena, Italy.
Bina BarbatoPathological Anatomy Unit, Department of Medical Biotechnology, Siena University Hospital, 53100 Siena, Italy.
Ilaria MonteleoneUnit of Diagnostic Imaging, Department of Medicine, Siena University Hospital, 53100 Siena, Italy.
Franco RovielloUnit of Surgical Oncology, Department of Medicine Surgery and Neurosciences, Siena University Hospital, 53100 Siena, Italy.ORCID 0000-0003-4122-1259
Sergio Antonio TripodiPathology Unit, Department of Oncology, Siena University Hospital, 53100 Siena, Italy.ORCID 0000-0003-2019-4730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic mucinous neoplasms (MCNs) of the pancreas are rare cystic tumors, accounting for approximately 2-5% of all pancreatic neoplasms. They predominantly occur in premenopausal women and are typically located in the body or tail of the pancreas. Due to their potential for malignant transformation, especially in cases associated with invasive carcinoma such as pancreatic ductal adenocarcinoma, early detection, complete surgical resection, and rigorous postoperative surveillance are essential. The occurrence of MCNs in male patients is exceedingly rare, comprising only about 2% of reported cases, and often resulting in preoperative diagnostic challenges. Molecular analyses have identified a strong association between KRAS mutations and disease progression in MCNs, underscoring their potential role as prognostic markers despite limited diagnostic utility. In this report, we present two additional cases of MCNs in male patients, highlighting their histopathological features and the ancillary investigations undertaken to support diagnosis.

Indexed as

Neoplasms, Cystic, Mucinous, and SerousPancreatic NeoplasmsHumansMalecase reportcystic mucinous neoplasmscystic tumorsKRASmalepancreas

Identifiers

PMID40558295
PMCPMC12192160

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.