Evidence map›Paper›PMID 40558294›Full record

ArticleCurrent oncology (Toronto, Ont.)2025

Renal Function Deterioration in Postoperative (Adjuvant) Chemotherapy for Colon Cancer-Real-Life Data.

Aleksandra Gładyś, Sylwia Kozak, Aleksander Jerzy Owczarek, Ewa Cedrych, Zofia Irena Niemir, Stanisław Łącki-Zynzeling, Anna Chudek, Izolda Mrochen-Domin, Iwona Gisterek-Grocholska, Jerzy Chudek

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aleksandra GładyśDepartment of Internal Diseases and Oncological Chemotherapy, Medical University of Silesia in Katowice, 40-029 Katowice, Poland.ORCID 0000-0002-5626-9960
Sylwia KozakDepartment of Internal Diseases and Oncological Chemotherapy, Medical University of Silesia in Katowice, 40-029 Katowice, Poland.ORCID 0000-0002-5226-5006
Aleksander Jerzy OwczarekHealth Promotion and Obesity Management Unit, Department of Pathophysiology, Medical University of Silesia in Katowice, 40-752 Katowice, Poland.ORCID 0000-0003-1179-6932
Ewa CedrychDepartment of Oncology, Katowice Oncology Center, 40-074 Katowice, Poland.ORCID 0000-0002-2720-9563
Zofia Irena NiemirDepartment of Nephrology, Transplantology and Internal Diseases, University of Medical Sciences, 60-355 Poznan, Poland.ORCID 0000-0003-1618-3596
Stanisław Łącki-ZynzelingDepartment of Internal Diseases and Oncological Chemotherapy, Medical University of Silesia in Katowice, 40-029 Katowice, Poland.ORCID 0000-0002-5827-8473
Anna ChudekHealth Promotion and Obesity Management Unit, Department of Pathophysiology, Medical University of Silesia in Katowice, 40-752 Katowice, Poland.ORCID 0000-0002-6140-4602
Izolda Mrochen-DominDepartment of Oncology, Katowice Oncology Center, 40-074 Katowice, Poland.ORCID 0009-0005-0566-7650
Iwona Gisterek-GrocholskaDepartment of Oncology and Radiotherapy, Medical University of Silesia in Katowice, 40-514 Katowice, Poland.ORCID 0000-0002-6320-0224
Jerzy ChudekDepartment of Internal Diseases and Oncological Chemotherapy, Medical University of Silesia in Katowice, 40-029 Katowice, Poland.ORCID 0000-0002-6367-7794

Funding

Operational Program Knowledge Education Development co-financed by the European Social Fund - The best of the best 4.0 The best of the best 4.0 to Aleksandra Gładyś and Sylwia Kozak
6 · The paper itself

Abstract

The knowledge concerning mild-to-moderate renal toxicity of adjuvant chemotherapy (CTH) in colon cancer patients is scarce. We retrospectively evaluated changes in the estimated glomerular filtration rate (eGFR) after three months of adjuvant treatment and the overall renal risk of the 6-month regimen in 145 patients who completed three months of therapy at three oncological centers. A decrease in eGFR of at least 1.5 mL/min/1.73 m

Indexed as

Colonic NeoplasmsKidneyAgedAged, 80 and overChemotherapy, AdjuvantFemaleGlomerular Filtration RateHumansMaleMiddle AgedRetrospective StudiesRisk Factorsadjuvant chemotherapycolon cancerkidney function deteriorationnephrotoxicity

Identifiers

PMID40558294
PMCPMC12191857

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.