Evidence map›Paper›PMID 40558278›Full record

ArticleCurrent oncology (Toronto, Ont.)2025

Increased Pre-Operative Lung Immune Prognostic Index Score Is a Prognostic Factor in Cases of Pathological T3 Renal Cell Carcinoma.

Hayato Hoshina, Toru Sugihara, Masayuki Kurokawa, Ei-Ichiro Takaoka, Satoshi Ando, Haruki Kume, Tetsuya Fujimura

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hayato HoshinaDepartment of Urology, Jichi Medical University Hospital, Shimotsuke 329-0498, Japan.ORCID 0009-0009-5067-0241
Toru SugiharaDepartment of Urology, Jichi Medical University Hospital, Shimotsuke 329-0498, Japan.ORCID 0000-0002-0901-3209
Masayuki KurokawaDepartment of Urology, Jichi Medical University Hospital, Shimotsuke 329-0498, Japan.
Ei-Ichiro TakaokaDepartment of Urology, Jichi Medical University Hospital, Shimotsuke 329-0498, Japan.
Satoshi AndoDepartment of Urology, Jichi Medical University Hospital, Shimotsuke 329-0498, Japan.
Haruki KumeDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8657, Japan.
Tetsuya FujimuraDepartment of Urology, Jichi Medical University Hospital, Shimotsuke 329-0498, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed the efficacy of the lung immune prognostic index (LIPI) in predicting the progression of pathological T3 renal cell carcinoma (RCC). The LIPI scores of patients with pathological T3 RCC were calculated in the pre- and post-operative phases. Patients were divided into zero-point, one-point, and two-point groups according to their LIPI score and into the upstage and non-upstage groups according to the pre- and post-operative increase in LIPI score. Overall survival (OS) was evaluated using Kaplan-Meier curves stratified by group. Univariate and multivariate analyses of OS were performed via Cox proportional hazard regression analysis. LIPI scores were calculated in 80 patients wherein blood sampling data were available. The upstage and non-upstage groups comprised eight and seventy-two patients, respectively. Kaplan-Meier curves showed a significant difference in the pre- to post-operative LIPI score upstage group. LIPI score change was a poor prognostic factor using univariate analysis (OS: hazard ratio (HR) = 4.10, 95% confidence interval (CI) = 1.07-15.61,

Indexed as

Carcinoma, Renal CellKidney NeoplasmsLungAdultAgedFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPreoperative PeriodPrognosisimmune biomarkerslung immune prognostic indexprognostic factorrenal cell carcinomaT3

Identifiers

PMID40558278
PMCPMC12192035

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.