Evidence map›Paper›PMID 40558252›Full record

ReviewCurrent oncology (Toronto, Ont.)2025

Predicting the Risk for Pathological Fracture in Bone Metastases.

Pavlos Altsitzioglou, Shinji Tsukamoto, Costantino Errani, Yasuhito Tanaka, Andreas F Mavrogenis

Abstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pavlos AltsitzioglouFirst Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, 15562 Athens, Greece.
Shinji TsukamotoDepartment of Orthopaedic Surgery, Nara Medical University, Kashihara 634-8521, Japan.ORCID 0000-0002-8419-2008
Costantino ErraniDepartment of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-4504-2867
Yasuhito TanakaDepartment of Orthopaedic Surgery, Nara Medical University, Kashihara 634-8521, Japan.ORCID 0000-0002-2300-611X
Andreas F MavrogenisFirst Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, 15562 Athens, Greece.ORCID 0000-0003-0807-0719

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 50-70% of patients with advanced cancer will experience bone metastases. The link between metastatic lesions and pathological bones is especially troubling since more metastases mean a higher chance of painful fractures, which can reduce mobility and often require surgery. Therefore, fracture risk predictions are essential for managing patients with bone metastases. However, the current methods for evaluating the risk of fractures are subjective, with low predictive value. This paper highlights how there being no effective comprehensive models for grouping patients by fracture risk due to skeletal metastases makes it harder to create personalized treatment plans; presents the methods currently used for objective evaluations of the pathological fracture risk in bone metastases; and discusses their pros and cons.

Indexed as

Bone NeoplasmsFractures, SpontaneousHumansRisk AssessmentRisk Factorsbone metastasesCTRAMirels’ scoring systempathological fractures

Identifiers

PMID40558252
PMCPMC12192531

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.