Evidence map›Paper›PMID 40558156›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Substitution of Proline Residues by 4-Fluoro-l-Proline Affects the Mechanism of the Proline-Rich Antimicrobial Peptide Api137.

Maren Reepmeyer, Andor Krizsan, Alexandra Brakel, Lisa Kolano, Jakob Gasse, Benjamin W Husselbee, Andrea J Robinson, Ralf Hoffmann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maren ReepmeyerInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Deutscher Platz 5, 04103 Leipzig, Germany.ORCID 0009-0008-5822-9584
Andor KrizsanInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Deutscher Platz 5, 04103 Leipzig, Germany.
Alexandra BrakelInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Deutscher Platz 5, 04103 Leipzig, Germany.ORCID 0000-0002-3354-1802
Lisa KolanoInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Deutscher Platz 5, 04103 Leipzig, Germany.ORCID 0000-0002-7962-2464
Jakob GasseInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Deutscher Platz 5, 04103 Leipzig, Germany.ORCID 0009-0006-0020-6019
Benjamin W HusselbeeSchool of Chemistry, Monash University, Wellington Road, Clayton, Melbourne, VIC 3800, Australia.ORCID 0009-0005-3430-1850
Andrea J RobinsonSchool of Chemistry, Monash University, Wellington Road, Clayton, Melbourne, VIC 3800, Australia.ORCID 0000-0003-3859-1312
Ralf HoffmannInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Deutscher Platz 5, 04103 Leipzig, Germany.ORCID 0000-0001-9932-5646

Funding

Federal Ministry of Education and Research (BMBF) number 16GW0299K
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Api137Fluoro-l-prolinemode of actionPrAMP

Identifiers

PMID40558156
PMCPMC12189828

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.