Evidence map›Paper›PMID 40558118›Full record

ArticleAdvances in respiratory medicine2025

Harnessing Natural Product Compounds to Target Dormancy Survival Regulator (DosR) in Latent Tuberculosis Infection (LTBI): An In Silico Strategy Against Dormancy.

Mandeep Chouhan, Mukesh Kumar, Vivek Dhar Dwivedi, Vivek Kumar Kashyap, Himanshu Narayan Singh, Sanjay Kumar

Abstract read
In one paragraph

Article in Advances in respiratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mandeep ChouhanBiological and Bio-Computational Lab, Department of Life Science, School of Basic Sciences and Research, Sharda University, Greater Noida 201310, UP, India.ORCID 0009-0007-9443-9784
Mukesh KumarDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi 110029, India.
Vivek Dhar DwivediBioinformatics Research Division, Quanta Calculus, Greater Noida 201310, UP, India.ORCID 0000-0003-0767-1328
Vivek Kumar KashyapDivision of Cancer Immunology and Microbiology, Medicine and Oncology Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
Himanshu Narayan SinghDepartment of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA.ORCID 0000-0003-4111-5165
Sanjay KumarBiological and Bio-Computational Lab, Department of Life Science, School of Basic Sciences and Research, Sharda University, Greater Noida 201310, UP, India.ORCID 0000-0001-6296-0291

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Dormancy occurs when

Indexed as

Antitubercular AgentsBacterial ProteinsBiological ProductsLatent TuberculosisMycobacterium tuberculosisComputer SimulationDNA-Binding ProteinsHumansMolecular Docking SimulationAntitubercular AgentsBacterial ProteinsBiological ProductsDNA-Binding ProteinsDosR protein, Mycobacterium tuberculosisdormancyDosRmolecular dynamics simulationstructure-based virtual screeningtuberculosis

Identifiers

PMID40558118
PMCPMC12190169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.