Evidence map›Paper›PMID 40557941›Full record

ArticleJournal of patient safety2025

The TRANS-SAFE Patient Safety Learning Laboratory: A Protocol for Systems Improvement for Psychosocial Safety in Transgender Care.

Tara N Cohen, Jennifer T Anger, Hanna Barton, Jill Blumenthal, Amanda Gosman, Falisha Kanji, Rai Khamisa, Jejo Koola, Priya Lewis, Maja Marinkovic and 7 more

Abstract read
In one paragraph

Article in Journal of patient safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tara N CohenDepartment of Surgery, Cedars-Sinai Medical Center, Los Angeles.ORCID 0000-0003-2137-6093
Jennifer T AngerDepartment of Urology, San Diego, UC San Diego Health, CA.
Hanna BartonBerbeeWalsh Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI.
Jill BlumenthalDepartment of Medicine, San Diego, UC San Diego School of Medicine.
Amanda GosmanDivision of Plastic Surgery, UC San Diego School of Medicine.
Falisha KanjiDepartment of Surgery, Cedars-Sinai Medical Center, Los Angeles.
Rai KhamisaUC San Diego Health, Gender Health Program.
Jejo KoolaDivision of Hospital Medicine, UC San Diego School of Medicine.
Priya LewisDivision of Plastic Surgery, UC San Diego School of Medicine.
Maja MarinkovicRady Children's Hospital-San Diego, Center for Gender-Affirming Care.
Bixby Marino-KibbeeRady Children's Hospital-San Diego, Center for Gender-Affirming Care.
Maxwell MooreDepartment of Urology, San Diego, UC San Diego Health, CA.
Kyle OkamuroTouro University California College of Osteopathic Medicine, Vallejo.
Shanaya SidhuUC San Diego School of Medicine.
Victor TrasvinaDepartment of Urology, San Diego, UC San Diego Health, CA.
Florin VaidaDivision of Biostatistics and Bioinformatics, UC San Diego Herbert Wertheim School of Public Health & Human Longevity Science.
Alan J CardDivision of Global Health Management & Policy, San Diego State University School of Public Health, San Diego, CA.

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Mitchell Smith · 1994 to 2026
$78.4M
AHRQ HHS R18 HS029299NIAID NIH HHS P30 AI036214
6 · The paper itself

Abstract

objectivesThis study aims to advance patient safety science by identifying and addressing the systemic causes of psychosocial harm among transgender and gender nonbinary (TGNB) individuals. The 4-year TRANS-SAFE patient safety learning laboratory (PSLL) will follow a 6-phase systems engineering approach to study ways to improve the safety of TGNB patients.

methodsThis study involves conducting a systematic scoping review, interviews with patients, providers, and community members, and observations of TGNB patient and provider experiences to identify determinants of avoidable patient suffering. In addition, the PSLL will provide financial support for pre-doctorate and post-doctorate research scholars in the TGNB community. Human-centered solutions will be co-designed to mitigate psychosocial harm among TGNB individuals. Interventions will be developed through engagement with stakeholders in an iterative process of co-design and evaluation.

resultsInterventions will be evaluated in real and simulated clinical environments for effectiveness, acceptability, usability, feasibility of implementation, and sustainability. A structural innovation of this PSLL is its focus on sustainment and dissemination, which will be facilitated through the development of a TRANS-SAFE certification process for health care organizations in partnership with the World Professional Association for Transgender Health (WPATH).

conclusionsThis PSLL will address a fundamental gap in the science and practice of patient safety by assessing and addressing psychosocial patient harm in a high-risk population that has been too often neglected in the patient safety literature.

Indexed as

Patient SafetySafety ManagementTransgender PersonsFemaleHumansMaleQuality Improvementavoidable patient sufferinghuman factorsmethodsnonbinarypatient safetypatient safety learning laboratorypsychosocial safetytransgender

Identifiers

PMID40557941
PMCPMC12354228

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.