Trial reportJournal of sleep research2026
The Effect of Digital Cognitive Behavioural Therapy for Insomnia in People With Co-Morbid Insomnia and Sleep Apnoea (COMISA): A Pilot Randomised Controlled Trial.
Trial report in Journal of sleep research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effectiveness of digital therapeutics in improving sleep quality: a systematic review and network meta-analysis.BMC medicine · 2026Pooled it
- The Effect of Digital Cognitive Behavioural Therapy for Insomnia in People With Co-Morbid Insomnia and Sleep Apnoea (COMISA): A Pilot Randomised Controlled Trial.Journal of sleep research · 2026Trial
- Management of adult insomnia in Australia: a joint position statement of the Australasian Sleep Association, Sleep Health Foundation, Royal Australian College of General Practitioners, Australian Psychological Society, Pharmaceutical Society of Australia, and Australian Primary Health Care Nurses Association.Sleep advances : a journal of the Sleep Research Society · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Co-morbid insomnia and sleep apnoea (COMISA) is a prevalent and debilitating condition. Cognitive behavioural therapy for insomnia (CBTi) is an effective but largely inaccessible treatment in patients with COMISA. We aimed to test a self-guided interactive digital CBTi program tailored for COMISA and insomnia alone. A pilot randomised controlled trial was conducted to investigate the effect of an interactive tailored digital CBTi program, versus digital sleep education (control) on symptoms of insomnia, depression, anxiety, sleepiness, fatigue, and maladaptive beliefs about sleep in people with COMISA. Online questionnaires were administered at baseline, 8 weeks, 16 weeks, and 24 weeks. Intent-to-treat mixed models and complete-case Fisher's exact analyses were used. Participants were 30 adults with COMISA (Age M[sd] = 61.0[10.3], 60% female, BMI = 33.5[6.5]). Compared to control, CBTi was associated with lower insomnia (M[95% CI] difference = 8.3[5.0-11.6], p < 0.001, d = 2.88), depression (3.7[1.0-6.5], p = 0.008, d = 1.66), anxiety (2.9[0.9-4.9], p = 0.005, d = 0.62), sleepiness (2.7[0.8-4.5], p = 0.007, d = 0.71), and maladaptive beliefs about sleep (13.9[5.7-22.2], p = 0.001, d = 1.16), but not fatigue (1.9[-1.2-4.9], p = 0.229, d = 0.68) at 8-week follow-up, controlling for baseline scores. The CBTi group experienced greater rates of insomnia remission (ISI < 8; 42%, vs. 0%, p = 0.012), and improvement (ISI reduction ≥ 6; 75% vs. 14%; p = 0.004) by 8-weeks. Improvements in the CBTi group were sustained by 24-weeks. This tailored digital CBTi program led to large and sustained improvements in insomnia, depression, anxiety, sleepiness, and maladaptive beliefs about sleep in people with COMISA. Trial Registration: This trial was prospectively registered on the Australian and New Zealand Clinical Trials Registry (ANZCTR, ACTRN12622001218785). https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=384648&isReview=true.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.